About: Biomarkets of Robustness of Metabolic - Hoemostasis for nutrigenomics

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About: Biomarkets of Robustness of Metabolic - Hoemostasis for nutrigenomics - derived Health claims made on food Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=7E10059
Description	The food and health relationship focuses on maintenance of optimal health, both in terms of physiology and new European legislation. Yet, most accepted biomarkers quantify (intermediate) disease endpoints or damage. This has led to major problems in demonstrating health benefits and establishing health claims, and blocks competitive economic and health developments in the food sector. BIOCLAIMS develops new biomarkers by exploiting the new concept of “health biomarkers” through quantification of the robustness of the homeostatic mechanisms involved in maintaining optimal health, based on the assumption that the ability to maintain homeostasis in a continuously challenged environment and changing physiology is key for healthy ageing. Mechanisms involved will be investigated during a series of food interventions in animal models and humans using “predisposed” conditions. Human models of presumed impaired robustness in maintaining metabolic and vascular health will be employed to study the responses of (en) The food and health relationship focuses on maintenance of optimal health, both in terms of physiology and new European legislation. Yet, most accepted biomarkers quantify (intermediate) disease endpoints or damage. This has led to major problems in demonstrating health benefits and establishing health claims, and blocks competitive economic and health developments in the food sector. BIOCLAIMS develops new biomarkers by exploiting the new concept of “health biomarkers” through quantification of the robustness of the homeostatic mechanisms involved in maintaining optimal health, based on the assumption that the ability to maintain homeostasis in a continuously challenged environment and changing physiology is key for healthy ageing. Mechanisms involved will be investigated during a series of food interventions in animal models and humans using “predisposed” conditions. Human models of presumed impaired robustness in maintaining metabolic and vascular health will be employed to study the responses of
Title	Biomarkets of Robustness of Metabolic - Hoemostasis for nutrigenomics - derived Health claims made on food (en) Biomarkets of Robustness of Metabolic - Hoemostasis for nutrigenomics - derived Health claims made on food
skos:notation	7E10059
http://linked.open...avai/cep/aktivita	Subvention of the projects of the Seventh Framework Programme of the European Community for research, technological development including demonstration activities (FP7) according to the Czech law 171/2007 Sb.
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/7E10059/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/7E10059/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2015-02-16 (xsd:date)
http://linked.open...i/cep/druhSouteze	RP - Spolufinancování programu ES
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	100525926
http://linked.open...ai/cep/hlavniObor	FB - Endokrinologie, diabetologie, metabolismus, výživa
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	health claims; biomarkers; nutrigenomics; homeostatic robustness (en)
http://linked.open...ep/partnetrHlavni	Fyziologický ústav AV ČR, v.v.i.
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	6 (xsd:int)
http://linked.open...enychVysledkuVRIV	6 (xsd:int)
http://linked.open...lneniVMinulemRoce	2013-03-22 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/MSMT-1838%2F2013-310
http://linked.open...iciPoslednihoRoku	2014
http://linked.open...atUdajeProjZameru	2014
http://linked.open...usZobrazovaneFaze	DRRVK
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2014-12-31 (xsd:date)
http://linked.open.../cep/vedlejsiObor	ED - Fyziologie
http://linked.open...ep/zahajeniReseni	2010-03-01 (xsd:date)
http://linked.open...tniCyklusProjektu	ZBBBK
http://linked.open...n/vavai/cep/vyzva	http://linked.opendata.cz/resource/domain/vavai/cep/vyzva/FP7-KBBE-2009-3
http://linked.open.../cep/klicoveSlovo	health claims biomarkers nutrigenomics
is http://linked.open...vavai/riv/projekt of	Direct comparison of health effects by dietary polyphenols at equimolar doses in wildtype moderate high-fat fed C57BL/6JOlaHsd mice BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology Augmenting energy expenditure by mitochondrial uncoupling: a role of AMP-activated protein kinase Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control Omega-3 phospholipids from fish suppress hepatic steatosis by integrated inhibition of biosynthetic pathways in dietary obese mice Preservation of Metabolic Flexibility in Skeletal Muscle by a Combined Use of n-3 PUFA and Rosiglitazone in Dietary Obese Mice
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E10059/2010/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E10059/2011/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E10059/2012/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E10059/2013/ico%3A67985823 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7E10059/2014/ico%3A67985823

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