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  • Compared with males of the C57BL/6N strain, female mice demonstrate increased capacity for adipocyte enlargement in response to a long-term HF feeding, which is associated with reduced adipose tissue macrophage infiltration and lower fat deposition in the liver, and with better insulin sensitivity. Our data suggest that adipose tissue expandability linked to adiponectin secretion might have a role in the sex differences observed in obesity-associated metabolic disorders
  • Compared with males of the C57BL/6N strain, female mice demonstrate increased capacity for adipocyte enlargement in response to a long-term HF feeding, which is associated with reduced adipose tissue macrophage infiltration and lower fat deposition in the liver, and with better insulin sensitivity. Our data suggest that adipose tissue expandability linked to adiponectin secretion might have a role in the sex differences observed in obesity-associated metabolic disorders (en)
Title
  • Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control
  • Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control (en)
skos:prefLabel
  • Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control
  • Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control (en)
skos:notation
  • RIV/67985823:_____/12:00377129!RIV13-GA0-67985823
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  • P(7E10059), P(GA303/08/0664), P(OC08008), Z(AV0Z50110509)
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  • 2
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  • 167642
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  • RIV/67985823:_____/12:00377129
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  • sex differences; inflammation; adipose tissue expandability; insulin sensitivity; mice (en)
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http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [B932DE10CDE6]
http://linked.open...i/riv/nazevZdroje
  • International Journal of Obesity
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  • 36
http://linked.open...iv/tvurceVysledku
  • Kopecký, Jan
  • Medříková, Daša
  • Bardová, Kristina
  • Janovská, Petra
  • Rossmeisl, Martin
  • Jílková, Zuzana
http://linked.open...ain/vavai/riv/wos
  • 000300321600012
http://linked.open...n/vavai/riv/zamer
issn
  • 0307-0565
number of pages
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  • 10.1038/ijo.2011.87
is http://linked.open...avai/riv/vysledek of
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