About: Ministry of Health’s Departmental Research and Development Programme III

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An Entity of Type : http://linked.opendata.cz/resource/domain/vavai/Aktivita, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/resource/domain/vavai/Aktivita
Title	Ministry of Health’s Departmental Research and Development Programme III (en) Resortní program výzkumu a vývoje Ministerstva zdravotnictví III (cs)
skos:notation	NT
http://linked.open...cea/pgm/FINCSTCEL	4448834
http://linked.open...ai/cea/pgm/XD_PGM	1099729115
http://linked.open...a/pgm/cilAktivity	Develop new diagnostic methods and procedures for as fast and accurate disease identification as possible. Acquire new knowledge about disease pathogenesis necessary to provide highly effective EBM-based treatment with emphasis on the support of molecular biology approaches. Develop research in the area of infectious disease prevention and mass incidence disease prevention. Analyze therapeutic treatment parameters to create conditions for efficient treatment with an impact on patient life quality. Gather data enabling continuous assessment of the population’s health status and its comparison with the status in other states of the European Union. Use research results for continuous education of physicians and other medical staff. (en) Vypracovat nové diagnostické metody a postupy, sloužící k co nejrychlejšímu a nejpřesnějšímu rozpoznání chorob. Získat nové poznatky o patogenezi chorob nutné pro zajištění vysoce efektivní léčby založené na EBM s důrazem na podporu molekulárně-biologických přístupů. Rozvíjet výzkum v oblasti prevence infekčních chorob a chorob hromadného výskytu. Analyzovat jednotlivé parametry léčebné péče tak, aby byly vytvořeny předpoklady pro efektivní léčbu provázanou i dopadem do kvality života pacienta. Získat údaje umožňující průběžné hodnocení vývoje zdravotního stavu populace a jeho srovnávání se stavem v ostatních státech Evropské unie. Využít výsledků výzkumu v průběžném vzdělávání lékařů i ostatních pracovníků ve zdravotnictví. (cs)
http://linked.open...isloUsneseniVlady	1133
http://linked.open...umSchvaleniVladou	2009-08-31 (xsd:date)
http://linked.open...a/pgm/rokUkonceni	2015
http://linked.open...a/pgm/rokZahajeni	2010
http://linked.open...a/pgm/typAktivity	P - Program
http://linked.open...inostNotifikaceEK	B - Program nepodléhá notifikaci (oznámení) Evropské komisi - aplikována bloková výjimka
http://linked.open...ai/cea/pgm/resort	Ministry of Health
is http://linked.open...avai/cep/aktivita of	Ochratoxin A – health risk assessment for selected population groups in the Czech Republic Profiling of neurosteroid conjugates and other acidic metabolites in body fluids and their perspective in clinical diagnostics Neonates with congenital anomalies of gastrointestinal tract: new approaches to prevention and diagnosis of necrotizing enterocolitis and sepsis Environmental and behavioral determinants of abdominal obesity and cardiometabolic health risks in Czech adolescents. Detection of optimal parameters of electrical neurostimulation in patients with overactive bladder. Speech, its impairment and cognitive performance in Parkinson's disease Examination of DNA instability in gametes, embryos and somatic cells following oncological therapy for improvement of reproductive success in treated patients. Development of vaccines against markers of cancer stem cells Diffuse large B-cell and follicular lymphoma - the analysis of prognostic factors and therapeutic strategies on patient´s outcome; Lymphoma Project in the Czech Republic. Identification of the genetic and molecular basis of rare genetic disorders using novel genomic methods. Molecular Characterization of B-cell Receptors and Their Relationship to Evolution of Gemonic Aberrations in Chronic Lymphocytic Leukemia Early identification of CLL patients with yet unselected p53 mutation Role of S-phase kinase-associated protein 2 in biology of prostate cancer stem cells and tumor progression Utilization of centrosomal proteins for prognostication and vaccinotherapy of chronic myeloid leukemia Animal and human serotonergic model of schizophrenia: validity evaluated by qEEG and fMRI. The prevalence and significance of mitochondrial metabolic defects in the myocardium of end-stage heart failure patients Analysis of bradykinesia and speech in Parkinson’s disease Information system for medical devices purchase monitoring Monitoring of tissue oxymetry and cerebral blood flow for detection and treatment of cerebral ischemia in patients after severe subarachnoid hemorrhage Optimization of detection and sentinel lymph nodes ultramicrostaging in endomerial carcinoma. The prevalence of HPV infections in the vaccinated population of women in the Czech Repuublic MiR137 and its influence on the production of mucin as a potential tool in early diagnosis of colorectal cancer or colorectal cancer relapse Immuno-pathogenetic backing data for the fibro-genesis for interstitial pulmonary processes, biomarkers of fibro-genesis Integrated genomic analysis of chronic lymphocytic leukemia (CLL) for genetic and clinical identification of subgroups with aberrations of selected chromosomes. Molecular pathophysiology of selected congenital disorders of erythropoiesis Expression of vascular endothelial growth factor VEGF-C/D and its significance for lymphangioneogenesis, nodal metastase and prognosis of salivary gland carcinomas. Complex biopsy-based diagnostics of inflammatory and viral myocardial disorders Diagnostics and operative treatment of displaced intraarticular fractures of the scapula New diagnostic approaches to Creutzfeldt-Jakob disease Clinical implication of circulating miRNA in monoclonal gammopathies Studies of anticancer effects of statins Primary cultures of human hepatocytes as a model for toxicological, pharmacological and biochemical studies in transplantation medicine. MRI diagnostic markers in Cushing´s disease Effect of ethanol and its principle metabolite acetaldehyde on cardiac inward rectifier potassium currents: a link to atrial fibrillation related to alcohol consumption? Prehospital Emergency Care Efficiency Metabolic response of organism in polytrauma patients Prediction of termination of pregnancy in women with serious hepatopathies Accuracy and impact of MR tractography in comparison to cortical and subcortical stimulation 1H MR Spectroscopy at 1.5T and 3T in Diagnostics of Prostate Carcinoma Relation of viral etiology of oropharyngeal tumors to the response rate of individual treatment modalities Genital warts, premalignant lesions and vulvar carcinoma diagnostic and therapeutical management optimalisation. Biomarkers of Bone Metastatic Disease Rationalization of the systemic treatment of age-related macular degeneration with rheohemapheresis New diagnostic algorithms for mitochondrial disorders in children Mapping of brain activity during the filling and emptying of the urinary bladder using the functional magnetic resonance imaging The importance of infiltrating immunocompetent cells for the development of head and neck squamous cell carcinoma Evaluation of usefulness of narrow-band imaging in detection of early recurrent laryngeal and hypopharyngeal tumours in patients after curative radiotherapy. The role of neurosteroids in the etiopathogenesis of multiple sclerosis Endoluminal radiofrequency ablation of tumors affecting the bile ducts PHARMACOGENETICS OF REMIFENTANIL IN PATIENTS WITH HYPERTENSION / PREECLAMPSIA UNDERGOING CAESAREAN DELIVERY UNDER GENERAL ANAESTHESIA Screening for genetic determinants of oligo/teratozoospermia in infertile men, informed by data from animal models Selected immunological and immunogenetic parameters in the prediction of graft versus host disease and the outcome of allogeneic haematopoietic stem cell transplantation Anthracycline cardiotoxicity – new possibilities of pharmacological cardioprotection and risks of combination with biological targeted anticancer treatment Foundation of serum bank based on long-term monitored patients with prostate cancer, offering the possibility of verification of any association between newly identified oncomarkers and the disease progression. A role of hereditary mutations of the PALB2 gene in breast, ovarian and pancreatic cancer development in the Czech Republic Diagnostic utility of hTERC and MYCC genes amplifications in initiations and development of cervical intraepithelial dysplasia and cervical carcinoma Origin of childhood leukaemias Cervical fluid - noninvasive prediction of histological chorioamnionitis and funisitis in pregnancies complicated by preterm prelabor rupture of membranes Genetic and factors of life style by children with markers of the metabolic syndrom and their dependents. Diagnostic and interference. -II Identifying agents of early-onset and late-onset nosocomial pneumonia in patients in intensive care through genetic analysis of bacterial DNA and determination of their distribution. Analysis of visceral pelvic fascia defects in women Molecular mechanisms of subclinical inflammation in adipose tissue and its role in the etiopathogenesis of type 2 diabetes mellitus Role of Genetic Variability in the Pathogenesis of Type 2 Diabetes Mellitus and Gestational Diabetes Impact of Cardiotocography evaluation by means of artificial inteligence on perinatal care The role of B cell lineage mitotic disruptions in multiple myeloma Molecular typing of syphilis-causing strains in the Czech Republic and detection of mutations leading to macrolide resistance Mapping of functional and anatomical correlates of obsessive-compulsive disorder and their relationship with clinical symptoms severity Standardization of dynamic tests of hypocorticalism Analysis of the genetic predisposition to the statin-induced side effects Computer analysis of speech expression, EEG records and MR tractography in children with developmental dysphasia Application of modern calculation methods for optimization of costs in health care Diagnostic markers and pathophysiological mechanisms of atypical parkinsonian syndromes PET / CT and ultrastructural changes of mitochondria as predictive factors for pancreatic cancer Intracranial EEG signal processing; epileptogenic zone identification in non-lesional refractory epilepsy patients Study of mediators of fibrotic processes in patients with diffuse lung diseases and their clinical application Microbiologic and genetic determinants of the onset and progression of periodontitis in type 1 and 2 diabetics and their reciprocal relationship to diabetes compensation Determination of functional state of the human circadian system and its changes in depression and bipolar disorder Chromogranin, metanephrines and thyroid factors in the differential diagnosis of neuroendocrine tumors directed to the medullary carcinoma of the thyroid gland and pheochromocytoma Standardized flow cytometry as a toll for fast and sensitive diagnostics in hematology – implementation of the Euroflow protocols in Czech Republic Phosphorus MR spectroscopy in vivo at 3T Selected picornaviruses in the pathogenesis of islet autoimmunity and type 1 diabetes Perioperative ischemia versus perioperative bleeding during non-cardiac surgery in cardiac patients : PRAGUE 14 Study The role of non-canonical Wnt signaling in molecular pathogenesis of chronic lymphocytic leukemia Molecular phenotyping of minimal kidney transplant injury and its prognostic value Diet Intervention in Subjects with Type 2 Diabetes: Effect of Meal Frequency and Composition on Glucose Metabolism and Symptoms of Metabolic Syndrome

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