About: Branch programm of research of the Ministry of Health

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rdf:type	http://linked.opendata.cz/resource/domain/vavai/Aktivita
Title	Branch programm of research of the Ministry of Health (en) Resortní program výzkumu a vývoje Ministerstva zdravotnictví (cs)
skos:notation	NR
http://linked.open...ai/cea/pgm/XD_PGM	254
http://linked.open...a/pgm/cilAktivity	Zkvalitnění péče o nemocné s kardiovaskulárními chorobami se snížením mortality. Optimalizace diagnostiky metabolických poruch. Snížení onkologické morbidity i mortality. Nové diagnostické metody neuropsychiatrických onemocnění a závislostí. Snížení dop adu muskuloskeletálních onemocnění, prevence úrazovosti. Molekulárně genetické faktory v patogenezi nemocí; zdokonalování prevence, diagnostiky a léčby vrozených vývojových vad a genetických onemocnění; zdokonalení péče o těhotné. Zdokonalení prevence, diagnostiky a terapie nejzávažnějších onemocnění v gynekologii a porodnictví, infekčních chorob a imunopatologických stavů. Modernizace chirurgické terapie. Zavádění progresivních zobrazovacích postupů v diagnostice; snížení zdravotních dopadů potenciál ních bezpečnostních rizik, zkracování doby hospitalizace. Efektivní nástroje podpory zdraví. Optimalizace systému péče o zdraví, zlepšení péče v oborech ošetřovatelství. Zkvalitňování péče o starší populaci.Přispět k prodloužení lidského života o 2 roky (cs) Improve quality of care for patients with cardiovascular conditions, reduction in mortality. Optimise recognition of metabolic disorders. Reduce oncological morbidity and mortality. Epidemiologically pick up neuropsychiatric diseases and addictions. Red uce the impact of musculoskeletal diseases. Health prevention of accidents. Widen the understanding of molecular genetic factors in the pathogenesis of diseases; improved prevention and early diagnostics and treatment of congenital malformations and ser ious genetic disorders. Improved care of pregnancy and prevention of pathological gravidity; improve quality of care at advanced age. Improve diagnostics, treatment of communicable diseases and immunopathological conditions. Tools of support of health. Modernize surgical therapy. Introduction of progressive imaging methods in diagnostics.Optimise the healthcare system. Improvement of the nursing theory.Reduction of the impact of potential security risks. Contribute a 2-year increase in life expectancy (en)
http://linked.open...isloUsneseniVlady	640
http://linked.open...umSchvaleniVladou	2003-06-30 (xsd:date)
http://linked.open...a/pgm/rokUkonceni	2009
http://linked.open...a/pgm/rokZahajeni	2004
http://linked.open...a/pgm/typAktivity	P - Program
http://linked.open...inostNotifikaceEK	J - Program nepodléhá oznámení (notifikaci) Evropské komisi z jiného důvodu
http://linked.open...ai/cea/pgm/resort	Ministry of Health
is http://linked.open...avai/cep/aktivita of	Oral health of preschool children, fluoride intake and parental attitudes and behavior towards prevention of dental caries of deciduous dentition Effect of reminiscence therapy on health status and quality of life in inhabitants of residential homes Role of renin-angiotensin system in pathophysiology of insulin resistance Verification and assessment of the dynamism of cognitive functions' profile in patients with depressive and schizophrenic disorders A Child on the Verges of Adulthood. A Population Study of Biological and Psychosocial Factors of Growth and Development of 15-Years Old Children. Outcome of gastric transposition for esophageal replacement in children. Factors influencing early and late morbidity, nutritional status, quality of life. Role of exaggerated inflammatory responses in brain damage during bacterial meniningitis and modalities of its modulation Analysis of transplantation activities, indications and results in the Czech Republic - National Stem Cell Transplantation Registry. Identification of inherited DNA polymorphisms in genes of testosterone synthetic pathway as factors of genetic predisposition to development of prostate cancer and their use in prevention and prognosis in Czech population Suprasegmental effects of selective posterior rhizotomy The impact of rehabilitation movement therapy on motor system activation in stroke patients Age - factor which modificate tissue response after surgical trauma Analysis of interactions among environmental and behavioral risk and protective factors of lung cancer with regard to prevent.approaches in publ.health Computer assisted knee anterior cruciate ligament reconstruction Detection of Chlamydia pneumoniae and CMV infection in atheroma plaques of peripheral arteries Apoptosis in osteoarthritis: Investigation of the expression of apoptosi modulating molecules and the presence of cell death in OA joint tissues. Transplantation of islets generated in vitro from stem cells of adult pancreas Effect of endoscopic treatment of grade 3-5 vesicoureteric reflux by dextranomer/hyaluronic acid copolymer compared with long-term prophylactic antibiotics. influence of platelet - rich plasma on bone regeneration after dental implant insertion. Dipeptidyl peptidase IV activity and/or structure homologues (DASH) in the brain tumors. Emerging factors in cancer pathogenesis? Transcranial Doppler signal changes after the surgery for craniosynostosis The pathogenesis of hypertensive end-organ damage in Ren-2 transgenic rats-the role of endothelin receptors (ETA and ETB) Proteomic analysis of pheochromocytoma cells Long-term morphological changes of the lower urogenital tract after urogynecolgical operations and their relationship to late complications. Prediction of changes in parameters of metabolic syndrome X related to changes of betahydroxybutate as a marker of ketegenesis in a study with physical activity at patients with metabolic syndrome X Glutamatergic theory of schizophrenia in animal and human models of disconnection tested by comparison with a population of schizophrenic patients The role of dental plaque bacteria in development of atherosclerotic changes in experimental model and clinical praxis New approaches to evaluation and prevention of toxicity of long-term pharmacotherapy of psoriasis with methotrexate: pharmacokinetics and influences of the genetic polymorphism of methylenetetrahydrofolate reductase and folate supplementation. Inhibitors of angiogenesis in multiple myeloma Microbial flora of the lower urogenital tract and occurrence of bacterial resistance with comparison to antibiotic prophylaxis to early infectious complications after urogynecological operations. Optimization of Prevention and Early Detection of Clolorectal carcinoma - Sreening Program The significance of inflammatory and oxidative stress biomarkers in exhaled breath condensate for progression of cystic fibrosis Polymorphism of genes for HLA-G and KIR as a possible marker of female fertility disorders - failure of embryotransfer and repeated pregnancy loss. New molecular markers of residual disease in acute myeloid leukemia patients and of disease progression in myelodysplastic patients, and prediction of STI-571 responsiveness in chronic myeloid leukemia patients at molecular level. Molecular causes of dispositions to alcoholism. The histopathology of middle ear, with the main topic of middle ear inflammation Mechanisms of imatinib resistance in patients with chronic myelogenous leukaemia Expression of molecular markers regulating hair follicle development and differentiation of trichogenic tumurs Ultrastructure of epiretinal membrane in diabetic cystoid macular oedema Analysis of QT dynamicity behaviour in relationship to the risk of sudden cardiac death HDL metabolism and its changes in patients with the meabolic syndrome after firate therapy DNA diagnostics of bacterial and viral infections of the cornea Assessment of different types of hormonal contraceptives´ effects on biochemical markers of cardiovascular risk among women with different smoking and nutritional habits and possibilities of their affection The expression of proinflammatory genes in patients with IgA nephropathy and their relation to the disease outcome Genetic Predisposition to Vascular Complications of Type 1 and Type 2 Diabetes Mellitus in Women Specific antibody response in patients with impaired immunity The significance of endothelial markers of activation in the prediction of subsequent development of preeclampsia Association of subclinical atherosclerosis with prevalence of venous thrombosis in thrombophilia. Diastolic dysfunction in diabetes mellitus II.type. The significance of the selected clinical, metabolic and endocrine parameters New approaches in the recanalization of acute intracranial artery occlusion: Comparison of the effectiveness and safety of intraarterial thrombolysis and sonothrombotrypsy versus conservative treatment External and genetic determinants of obesity The role of pharmacies in the prevention of infectious diseases in injecting drug users in the Czech republic. Measurement of the concentration of cytostatics in the vitreous cavity of rabbits eye ball after trancorneal and subconjunctival administration Rheopheresis as the metod of systemic therapy in age-related macular degeneration Main genetic causes and their modifiers in the pathogenesis of thyroid cancer Utilisation of genetical analysis to the diagnostics of human cytomegalovirus infection in immunodeficient patients Genetic variability of pentose phosphate pathway as a modulating factor of the onset and progression of diabetic nephropathy Anticancer treatment toxicity reduction using the intensity-modulated radiation therapy Ipsilateral fractures of the proximal femur and the femoral shaft Risc factors of atherosclerosis in cancer patients Polymorphisms in FSH- and androgen receptor genes and in the CFTR gene in the pathogenesis of severe reproductive disorders and in pharmacogenetic prevention of ovarian hyperstimulation syndrome The role of visceral adipose tissue in ethiopathogenesy of metabolic syndrome investigated on a level of molecular genetic characteristics of tissue Glucose homeostasis disorders and pancreatic cancer: new genetic and nutrition markers related to its occurrence and prognosis Detection and analysis of genomic variations in selected oncogenes and tumor supressor genes in patients with chronic pancreatitis and pancreatic cancer and their use in early diagnostic and therapeutic process. Occurence of myocardial ion channel genes polymorphisms in relationship to sudden cardiac death in patients with structural heart disease The nature of acute and chronic humoral renal graft rejection at the level of molecular biology Vaccination against hepatitis B in newborns of HBsAg positive mothers - long-term evaluation of protection Flexible endoscopy for minimally invasive treatment of gastroesophageal reflux disease in randomized comparative study with classic surgery Role of cytokines in perioperative process of surgical treatment patients with pulmonary hypertension Posttransplant function of ischemically impaired organs (pancreas, kidney, islets) preserved by oxygenated perfluorocarbon (PFC). Genetic, biochemistry in correlation biorytms in children with ADHD Demographic analysis of bio-social factors of breastfed children in the Czech Republic in 2000-2004. Indication of extracranial-intracranial bypasses in patients with carotid occlusion - assessment of recurrent stroke risk by the combined examination of cerebral vasomotor reactivity with transcranial Doppler sonography and functional magnetic resonance Consequences of chronic intake of caffeine during early ontogeny on brain excitability Molecular pathology and pathophysiology of neurodegenerative diseases accompanied by movement disorders Comparison of the therapeutic effect of various surgical procedures managing descensus of anterior vaginal segment, with and without using a synthetic implant Activation of fybrinolytic system using continual sonography monitoring in acute stroke patients and in volunteers AML1 gene and HOX genes in pathogenesis of childhood acute leukaemias Complex liposomal forms of photosentitizers for experimental photodynamic therapy of tumors Human Stem Cells Differentiation in Chondrocytes, Cartilage Mechanical Property - Experimental Study, Part I. Detection of neuroanatomical risk factors for bipolar disorder Prediction of chemosensitivity / chemoresistance to the target therapy of breast carcinoma with amplification of the Her-2 gene, based on the analysis of Akt signal pathway and serial quantitative testing for serum HER-2/neu extracellular domain Dyslipidemia classification based on concentration of apolipoprotein B and triglycerides. Association of dyslipidemic phenotypes with indices of insulin resistance, inflammation and thrombosis, subclinical and clinical atherosclerosis and DNA markers. Diastolic heart failure: diagnosis, pathophysiologic mechanisms and their impact on clinical outcomes Longitudinal prospective study on carcinogenic risk in workers exposed to dust with content of crystalline form of silica dioxide in the Czech Republic. Difference in the behaviour of the freshly isolated and cryo-preserved ovarian cancer cells and its clinical significance

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