About: Neurotoxicity of NAAG in vivo is sensitive to NMDA antagonists and mGluR II ligands.

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About: Neurotoxicity of NAAG in vivo is sensitive to NMDA antagonists and mGluR II ligands. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The paper has two specific aims : (l) to investigate an ability ofintracerebroventricularly (ICV) infused NAAG to induce neurodegene-ration in subregions of rat hippocampal formation and (2) to test theability of NMDA receptor antagonists and mGluR ligands to prevent theneurotoxic actions of NAAG. NAAG-induced neurodegeneration is lesssevere than that induced by quinolinate and can be inhibited by NMDAreceptor antagnonists and also by an mGluR II agoinst, DCG IV. The paper has two specific aims : (l) to investigate an ability ofintracerebroventricularly (ICV) infused NAAG to induce neurodegene-ration in subregions of rat hippocampal formation and (2) to test theability of NMDA receptor antagonists and mGluR ligands to prevent theneurotoxic actions of NAAG. NAAG-induced neurodegeneration is lesssevere than that induced by quinolinate and can be inhibited by NMDAreceptor antagnonists and also by an mGluR II agoinst, DCG IV. (en)
Title	Neurotoxicity of NAAG in vivo is sensitive to NMDA antagonists and mGluR II ligands. Neurotoxicity of NAAG in vivo is sensitive to NMDA antagonists and mGluR II ligands. (en)
skos:prefLabel	Neurotoxicity of NAAG in vivo is sensitive to NMDA antagonists and mGluR II ligands. Neurotoxicity of NAAG in vivo is sensitive to NMDA antagonists and mGluR II ligands. (en)
skos:notation	RIV/67985823:_____/00:20000101!RIV/2003/AV0/A20003/N
http://linked.open.../vavai/riv/strany	3651;3654
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA309/99/0211), P(KSK2011602), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	16
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Šťastný, František Pliss, Lioudmila
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	719100
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/00:20000101
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	N/A (en)
http://linked.open.../riv/klicoveSlovo	N/A
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[C59606857D91]
http://linked.open...i/riv/nazevZdroje	NeuroReport
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Localization, distribution and function of glutamate receptor in brain capillary barrier Brain and nervous systems
http://linked.open...UplatneniVysledku	2000
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Šťastný, František Balcar, V. J. Fitzgibbon, T. Pliss, Lioudmila
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0959-4965
number of pages	4 (xsd:int)

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