About: Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Thanks to the stability, good availability, stereoselectivity and broad substrate specificity, oligosacharide synthesis catalyzed by glycosidases represents an elegant way to komplex carbohydrate structures. Two approaches to glycosidase catalysis are presented: i) the use of structurally modified substrates that carry various functional moieties in the molecule, and ii) the design of mutant glycosidases void of hydrolytic activity. Products of glycosidase catalyzed synthesis are applicable in a range of areas such as immunology, therapy of Alzheimer’s or Parkinson’s diseases and the synthesis of neoglycoproteins Thanks to the stability, good availability, stereoselectivity and broad substrate specificity, oligosacharide synthesis catalyzed by glycosidases represents an elegant way to komplex carbohydrate structures. Two approaches to glycosidase catalysis are presented: i) the use of structurally modified substrates that carry various functional moieties in the molecule, and ii) the design of mutant glycosidases void of hydrolytic activity. Products of glycosidase catalyzed synthesis are applicable in a range of areas such as immunology, therapy of Alzheimer’s or Parkinson’s diseases and the synthesis of neoglycoproteins (en)
Title	Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short (en)
skos:prefLabel	Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short (en)
skos:notation	RIV/61388971:_____/11:00360713!RIV12-AV0-61388971
http://linked.open...avai/predkladatel	Mikrobiologický ústav AV ČR, v.v.i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP203/09/P024), P(LC06010), P(OC09045), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Bojarová, Pavla Křen, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	201388
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/11:00360713
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Carbohydrate; Enzymatic synthesis; Glycosidase (en)
http://linked.open.../riv/klicoveSlovo	Enzymatic synthesis Glycosidase Carbohydrate
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[031266DAC9A6]
http://linked.open...i/riv/nazevZdroje	Chimia
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Center of Biocatalysis and Biotransformation Selective enzymatic oxidations and deracemizations of natural products and biomolecules Synthesis of immunoactive glycosides by beta-N-acetylhexosaminidases
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	65
http://linked.open...iv/tvurceVysledku	Bojarová, Pavla Křen, Vladimír
http://linked.open...ain/vavai/riv/wos	000287981400013
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology
issn	0009-4293
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.2533/chimia.2011.65
is http://linked.open...avai/riv/vysledek of	Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short

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