About: BCR/ABL1 Fusion Protein     Goto   Sponge   Distinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • BCR/ABL1 Fusion Protein
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • BCR/ABL1 Fusion Protein
UMLS_CUI
  • C0004891
Legacy_Concept_Name
  • BCR-ABL_Oncoprotein
FULL_SYN
  • BCR ABL Fusion ProteinSYNCI
  • BCR/ABL Fusion ProteinSYNCI
  • BCR-ABL1 Fusion ProteinSYNCI
  • BCR/ABL1 Fusion ProteinPTNCI
  • BCR/ABL Chimeric ProteinSYNCI
  • BCR/ABLABNCI
  • BCR-ABL fusion proteinPTNCI-GLOSSCDR0000641107
  • BCR-ABL OncoproteinSYNCI
  • BCR/ABL OncoproteinSYNCI
  • BCR-ABL Protein Tyrosine KinaseSYNCI
  • Breakpoint Cluster Region/Tyrosine-Protein Kinase ABL1 Fusion ProteinSYNCI
DEFINITION
  • A fusion protein encoded by the BCR/ABL1 fusion gene. This protein is comprised of the N-terminus of the breakpoint cluster region protein fused to almost the entire tyrosine-protein kinase ABL1 protein.NCI
DesignNote
  • The BCR/ABL1 fusion protein is a constitutively activated tyrosine kinase and has a cytoplasmic localization, in contrast with the mostly nuclear localization of the tyrosine-protein kinase ABL1 protein. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
code
  • C16325
sameAs
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