About: Pseudomonas Exotoxin Immunoconjugate

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Attributes	Values
rdf:type	Class
rdfs:label	Pseudomonas Exotoxin Immunoconjugate
rdfs:subClassOf	Immunotoxins
Semantic_Type	Pharmacologic Substance Chemical Viewed Structurally
Preferred_Name	Pseudomonas Exotoxin Immunoconjugate
UMLS_CUI	C2698914
Legacy_Concept_Name	Pseudomonas_Exotoxin_Immunoconjugate
FULL_SYN	Pseudomonas aeruginosa Exotoxin A ConjugateSYNCI Pseudomonas Exotoxin ImmunoconjugatePTNCI PE ImmunoconjugateSYNCI
DEFINITION	An immunotoxin containing epitope of Pseudomonas exotoxin (PE) with immunotherapeutic property. PE, a peptide toxin of 613 amino acids, consists of 3 functional domains: an amino-terminal receptor-binding domain, a middle translocation domain, and a carboxyl-terminal ADP-ribosylation domain. The last 5 carboxyl-terminal amino acids, Arg-Glu-Asp-Leu-Lys, are critical for its cytotoxic action.NCI
code	C78532
is rdf:first of	nodeID://b739067 nodeID://b739068
is rdfs:subClassOf of	LMB-7 Immunotoxin Interleukin-4 PE38kdel Immunotoxin LMB-9 Immunotoxin LMB-1 Immunotoxin Cintredekin Besudotox Monoclonal Antibody OVB3-PE TGFa-PE38 Immunotoxin BR96 sFv-PE40 G28-5 sFv-PE40 BL22 Immunotoxin TP40 Immunotoxin SS1(dsFv)-PE38 Immunotoxin Moxetumomab Pasudotox

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