About: LMB-7 Immunotoxin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • LMB-7 Immunotoxin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • LMB-7 Immunotoxin
NSC_Code
  • 658931
  • 659639
UMLS_CUI
  • C0296314
ALT_DEFINITION
  • A toxic substance linked to an antibody that attaches to tumor cells and kills them.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42683
PDQ_Closed_Trial_Search_ID
  • 42683
Legacy_Concept_Name
  • LMB-7_Immunotoxin
FULL_SYN
  • B3(Fv)-PE38SYNCI
  • LMB-7 immunotoxinPTNCI-GLOSSCDR0000045541
  • B3(Fv)-PE38 ImmunotoxinSYNCI
  • HB21(Fv)PE40SYNCI
  • LMB-7 ImmunotoxinPTNCI
  • Immunotoxin LMB-7SYNCI
  • Immunotoxin LMB-7SYDTPNSC0659639
  • LMB-7 (Single-Chain Immunotoxin)SYNCI
DEFINITION
  • A single chain chimeric protein consisting of a monoclonal antibody fragment attached to a portion of the Pseudomonas exotoxin A. LMB-7 immunotoxin attaches to B3, a Lewis Y-related carbohydrate epitope on some solid tumor cells. The antibody attaches to the cell and the exotoxin inhibits protein synthesis by inactivating elongation factor 2. (NCI04)NCI
code
  • C1619
http://linked.open...y/mesh/hasConcept
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