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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pazopanib
rdfs:subClassOf
Has_Salt_Form
Has_Target
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pazopanib
UMLS_CUI
  • C1831796
CAS_Registry
  • 444731-52-6
  • 790713-33-6
FDA_UNII_Code
  • 7RN5DR86CK
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to treat kidney cancer and is being studied in the treatment of other types of cancer. It may prevent the growth of new blood vessels that tumors need to grow. It is a type of protein tyrosine kinase inhibitor and a type of antiangiogenesis agent.NCI-GLOSS
Chemical_Formula
  • C21H23N7O2S
Legacy_Concept_Name
  • Pazopanib_Base
FULL_SYN
  • PAZOPANIBPTFDA7RN5DR86CK
  • GW786034PTNCI-GLOSSCDR0000321375
  • Benzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-SNNCI
  • GW786034CNNCI
  • PazopanibPTNCI
DEFINITION
  • A small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.NCI
code
  • C74547
http://linked.open...y/mesh/hasConcept
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