About: Piroxantrone Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Piroxantrone Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Piroxantrone Hydrochloride
UMLS_CUI
  • C2347520
CAS_Registry
  • 105118-12-5
FDA_UNII_Code
  • PS51OZG63Z
Contributing_Source
  • FDA
Chemical_Formula
  • C21H25N5O4.2HCl
Legacy_Concept_Name
  • Piroxantrone_Hydrochloride
FULL_SYN
  • Piroxantrone HydrochloridePTNCI
  • PIROXANTRONE HYDROCHLORIDEPTFDAPS51OZG63Z
DEFINITION
  • The hydrochloride salt form of piroxantrone, an anthrapyrazole antineoplastic antibiotic. Piroxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. Although less cardiotoxic than doxorubicin, this agent exhibits a narrow spectrum of antineoplastic activity.NCI
code
  • C72829
is Has_Salt_Form of
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