About: Amonafide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Amonafide
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Amonafide
UMLS_CUI
  • C0126606
CAS_Registry
  • 69408-81-7
FDA_UNII_Code
  • 1Q8D39N37L
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called topoisomerase inhibitors and intercalating agents.NCI-GLOSS
Chemical_Formula
  • C16H17N3O2
Legacy_Concept_Name
  • Amonafide_Base
FULL_SYN
  • BenzisoquinolinedioneSYNCI
  • 1H-benz(de)isoquinoline-1,3(2H)-dione, 5-amino-2-(2-(dimethylamino)ethyl)SNNCI
  • BenzisoquinolinedioneSYDTPNSC0308847
  • BIDAABNCI
  • AMONAFIDEPTFDA1Q8D39N37L
  • AmonafideSYDTPNSC0308847
  • M-FA-142CNNCI
  • AmonafidePTNCI
  • amonafidePTNCI-GLOSSCDR0000350223
DEFINITION
  • An imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis.NCI
code
  • C71628
http://linked.open...y/mesh/hasConcept
is Has_Free_Acid_Or_Base_Form of
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