About: Carbohydrate-Containing Dendrimers in Biomedical Applications

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Glycodendrimers are (regularly) branched structures containing carbohydrates. Many of these compounds with various composition and structure are mentioned; as well as, their practical applications spanning from drug and gene deliveries, synthetic vaccines, prevention of pathological processes caused by bacteria and viruses, etc. A dendrimeric state, physicochemical properties of dendrimers, and general consequences are reviewed with emphasis to a cluster effect and multivalency. Two main approaches of glycodendrimer syntheses - convergent and divergent - are described. Since glycopeptide dendrimers suppress lectin-carbohydrate interactions, glycodendrimeric libraries provide potent inhibitors of bacterial adhesion and biofilm formation. Glycodendrimers are (regularly) branched structures containing carbohydrates. Many of these compounds with various composition and structure are mentioned; as well as, their practical applications spanning from drug and gene deliveries, synthetic vaccines, prevention of pathological processes caused by bacteria and viruses, etc. A dendrimeric state, physicochemical properties of dendrimers, and general consequences are reviewed with emphasis to a cluster effect and multivalency. Two main approaches of glycodendrimer syntheses - convergent and divergent - are described. Since glycopeptide dendrimers suppress lectin-carbohydrate interactions, glycodendrimeric libraries provide potent inhibitors of bacterial adhesion and biofilm formation. (en)
Title	Carbohydrate-Containing Dendrimers in Biomedical Applications Carbohydrate-Containing Dendrimers in Biomedical Applications (en)
skos:prefLabel	Carbohydrate-Containing Dendrimers in Biomedical Applications Carbohydrate-Containing Dendrimers in Biomedical Applications (en)
skos:notation	RIV/68378050:_____/11:00361112!RIV12-AV0-68378050
http://linked.open...avai/predkladatel	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/07/1517), P(IAA400550702), Z(AV0Z40550506), Z(AV0Z50520514)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Reiniš, Milan
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	189148
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/11:00361112
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	dendrimers; drug delivery; gene delivery; glycobiology; glycoclusters (en)
http://linked.open.../riv/klicoveSlovo	dendrimers drug delivery gene delivery glycobiology glycoclusters
http://linked.open...ontrolniKodProRIV	[AC3DB2D81FC7]
http://linked.open...i/riv/mistoVydani	Shawbury
http://linked.open...i/riv/nazevZdroje	Polysaccharides in Medicinal and Pharmaceutical Applications
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...v/pocetStranKnihy	408 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Chemical syntheses of fluorescence labeled mouse prion proteins using chemical ligations and investigation of their properties Spectroscopic and theoretical methods for non-covalent molecular interactions
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Ježek, Jan Reiniš, Milan Šebestík, Jaroslav
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství Molekulárně genetické a buněčné základy klíčových biologických procesů: genová exprese, onkogeneze, replikace virů, imunita a vývoj organismů
number of pages	13 (xsd:int)
http://purl.org/ne...btex#hasPublisher	iSmithers
https://schema.org/isbn	978-1-84735-437-2
is http://linked.open...avai/riv/vysledek of	Carbohydrate-Containing Dendrimers in Biomedical Applications Carbohydrate-Containing Dendrimers in Biomedical Applications

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