About: Complete genome sequence and analysis of the Streptomyces aureofaciens phage mu1/6

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Description	The entire double-stranded DNA genome of the Streptomyces aureofaciens phage mu1/6 was sequenced and analyzed. Its size is 38.194 kbp with an overall molar G+C content of 71.2 %. Fifty-two potential open reading frames were identified, divided into two oppositely transcribed regions. In the left arm of the mu1/6 genome, an identified putative integrase and possible regulation proteins were identified. The rightwards transcribed region contains genes organized into apparently four functional units responsible for: (i) replication, (ii) DNA packaging and head assembly, (iii) tail morphogenesis, and (iv) lysis. Comparative analysis with three complete genomes of streptomycete phages revealed resemblance with respect to the organization of their genes into functional modules. Closer relationship was observed only between mu1/6 and S. venezuelae phage VWB. The entire double-stranded DNA genome of the Streptomyces aureofaciens phage mu1/6 was sequenced and analyzed. Its size is 38.194 kbp with an overall molar G+C content of 71.2 %. Fifty-two potential open reading frames were identified, divided into two oppositely transcribed regions. In the left arm of the mu1/6 genome, an identified putative integrase and possible regulation proteins were identified. The rightwards transcribed region contains genes organized into apparently four functional units responsible for: (i) replication, (ii) DNA packaging and head assembly, (iii) tail morphogenesis, and (iv) lysis. Comparative analysis with three complete genomes of streptomycete phages revealed resemblance with respect to the organization of their genes into functional modules. Closer relationship was observed only between mu1/6 and S. venezuelae phage VWB. (en) Byla stanovena úplná nukleotidová sekvence genomu fága mu1/6 ze Streptomyces aureofaciens. Velikost genomu je 38 194 bazí s celkovým obsahem bazí G+C 71,2 procent. Bylo nalezeno 52 potenciálních otevřených rámců, které jsou rozděleny do dvou opačně orientovaných operonů. V levém operonu byly nalezeny geny kodující integrasu a regulační faktory. Pravá oblast genomu obsahovala geny, které byly rozděleny do čtyř jednotek: (i) replikace, (ii) pakážování DNA a složení hlavy fága, (iii) morfogeneze nohy fága a (iv) lyze. Byla odhalena podobnost mezi fágem mu1/6 a fágem VWB z S. venezuelae. Byla také vytýčena okrajová podobnost mezi fágy infikujícími bakterie druhu Streptomyces. (cs)
Title	Complete genome sequence and analysis of the Streptomyces aureofaciens phage mu1/6 Complete genome sequence and analysis of the Streptomyces aureofaciens phage mu1/6 (en) Úplná genomová sekvence a analýza fága mu1/6 ze Streptomyces aureofaciens (cs)
skos:prefLabel	Complete genome sequence and analysis of the Streptomyces aureofaciens phage mu1/6 Complete genome sequence and analysis of the Streptomyces aureofaciens phage mu1/6 (en) Úplná genomová sekvence a analýza fága mu1/6 ze Streptomyces aureofaciens (cs)
skos:notation	RIV/68378050:_____/07:00310141!RIV09-AV0-68378050
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0520), Z(AV0Z50520514)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Vlček, Čestmír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	414500
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/07:00310141
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	phage; genome; streptomyces (en)
http://linked.open.../riv/klicoveSlovo	streptomyces genome phage
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[9E2C57849BFE]
http://linked.open...i/riv/nazevZdroje	Folia Microbiologica
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Center for Applied Genomics
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	52
http://linked.open...iv/tvurceVysledku	Vlček, Čestmír Kokavec, J. Klucar, L. Farkasovská, J. Godány, A.
http://linked.open...ain/vavai/riv/wos	000250290500005
http://linked.open...n/vavai/riv/zamer	Molekulárně genetické a buněčné základy klíčových biologických procesů: genová exprese, onkogeneze, replikace virů, imunita a vývoj organismů
issn	0015-5632
number of pages	12 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Complete genome sequence and analysis of the Streptomyces aureofaciens phage mu1/6

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