About: Ribosomal genes in focus: new transcripts label the dense fibrillar components and form clusters indicative of ('Christmas trees)' in situ.

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About: Ribosomal genes in focus: new transcripts label the dense fibrillar components and form clusters indicative of ('Christmas trees)' in situ. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The organization of transcriptionally active ribosomal genes in animal cell nucleoli is investigated in this study. We demonstrate that each nucleolar focus observed by LM corresponds, on the EM level, to an individual fibrillar center (FC) and surrounding dense fibrillar components (DFCs). The EM data identify the DFC as the nucleolar subcompartment in which rRNA synthesis takes place. Intense and unambiguous clustered immunogold signal of nascent transcripts is strongly indicative of nascent 'Christmas trees' of rRNA associated with individual rDNA genes. The organization of transcriptionally active ribosomal genes in animal cell nucleoli is investigated in this study. We demonstrate that each nucleolar focus observed by LM corresponds, on the EM level, to an individual fibrillar center (FC) and surrounding dense fibrillar components (DFCs). The EM data identify the DFC as the nucleolar subcompartment in which rRNA synthesis takes place. Intense and unambiguous clustered immunogold signal of nascent transcripts is strongly indicative of nascent 'Christmas trees' of rRNA associated with individual rDNA genes. (en)
Title	Ribosomal genes in focus: new transcripts label the dense fibrillar components and form clusters indicative of ('Christmas trees)' in situ. Ribosomal genes in focus: new transcripts label the dense fibrillar components and form clusters indicative of ('Christmas trees)' in situ. (en)
skos:prefLabel	Ribosomal genes in focus: new transcripts label the dense fibrillar components and form clusters indicative of ('Christmas trees)' in situ. Ribosomal genes in focus: new transcripts label the dense fibrillar components and form clusters indicative of ('Christmas trees)' in situ. (en)
skos:notation	RIV/68378041:_____/02:19023042!RIV/2003/GA0/A19003/N
http://linked.open.../vavai/riv/strany	743;748
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA304/00/1481), P(GA304/00/D035), P(GA304/01/0729), P(IAA5039103), Z(AV0Z5039906), Z(MSM 111100003)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Mašata, Martin Večeřová, Jaromíra Raška, Ivan Malinský, Jan Koberna, Karel Kalmárová, Markéta Pliss, Artem
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	662401
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/02:19023042
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cell nucleolus; rRNA genes; ribosomal RNA (en)
http://linked.open.../riv/klicoveSlovo	cell nucleolus ribosomal RNA rRNA genes
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[E9589E4C2604]
http://linked.open...i/riv/nazevZdroje	Journal of Cell Biology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Dynamic structure and function in the cell nucleus Deconvolution image restoration in the studies of the cell nucleus architecture Large scale organization of chromatin Dynamics of Spliceosome assembly
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	157
http://linked.open...iv/tvurceVysledku	Mašata, Martin Raška, Ivan Malínský, Jan Koberna, Karel Fialová, Markéta Pliss, Artem Večeřová, Jaromíra Bednár, J.
http://linked.open...n/vavai/riv/zamer	The molecular and cellular basis of selected human diseases, mechanisms of normal and pathological function, principles of diagnosis and therapy http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111100003
issn	0021-9525
number of pages	6 (xsd:int)

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