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  • Exposure to ultraviolet (UV) irradiation has detrimental effects on skin accompanied by the increased metabolism of hyaluronan (HA). Immortalized human keratinocytes (HaCaT) were irradiated by a single dose of UVB and immediately treated with HA for 6 and 24 h. The expressions of HA synthase-3 and hyaluronidase-3 were not significantly odulated by UV irradiation. In contrast, HA significantly suppressed UVB-induced proinflammatory cytokine release including interleukin-6 and interleukin-8.
  • Exposure to ultraviolet (UV) irradiation has detrimental effects on skin accompanied by the increased metabolism of hyaluronan (HA). Immortalized human keratinocytes (HaCaT) were irradiated by a single dose of UVB and immediately treated with HA for 6 and 24 h. The expressions of HA synthase-3 and hyaluronidase-3 were not significantly odulated by UV irradiation. In contrast, HA significantly suppressed UVB-induced proinflammatory cytokine release including interleukin-6 and interleukin-8. (en)
Title
  • Hyaluronan minimizes effects of UV irradiation on human keratinocytes
  • Hyaluronan minimizes effects of UV irradiation on human keratinocytes (en)
skos:prefLabel
  • Hyaluronan minimizes effects of UV irradiation on human keratinocytes
  • Hyaluronan minimizes effects of UV irradiation on human keratinocytes (en)
skos:notation
  • RIV/68081707:_____/11:00359410!RIV12-AV0-68081707
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA305/08/1704), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika
  • 4
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  • 203026
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/11:00359410
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • hyaluronan; keratinocyte; ultraviolet light (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [74C8E7515CF6]
http://linked.open...i/riv/nazevZdroje
  • Archives of Dermatological Research
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  • 303
http://linked.open...iv/tvurceVysledku
  • Kubala, Lukáš
  • Crhák, Tomáš
  • Dvořáková, J.
  • Hašová, M.
  • Muthný, T.
  • Velebný, V.
  • Šafránková, Barbora
http://linked.open...ain/vavai/riv/wos
  • 000289728300007
http://linked.open...n/vavai/riv/zamer
issn
  • 0340-3696
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00403-011-1146-8
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