About: Investigation of the in vitro metabolism of the analgesic flupirtine

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The in vitro metabolism of flupitrine and its metabolite D13223, a centrally acting analgesic with muscle tone-reducing activity, was studied. The metabolism of these drugs is connected with their redox chemistry. The redox behavior was studied by cyclic voltammetry and compare with the potential role of various oxidative enzymes. The in vitro metabolism of flupitrine and its metabolite D13223, a centrally acting analgesic with muscle tone-reducing activity, was studied. The metabolism of these drugs is connected with their redox chemistry. The redox behavior was studied by cyclic voltammetry and compare with the potential role of various oxidative enzymes. (en) Byl studován metabolismus analgetika flupirtinu a jeho analogu D13223, které centrálně regulují svalové napětí. Jejich aktivita souvisí s redoxním chováním. To bylo studováno pomocí cyklické voltametrie a následně byl oxidativní metabolismus studován na řadě modelových, oxidativní enzymy zahrnujících, systémů. (cs)
Title	Investigation of the in vitro metabolism of the analgesic flupirtine Studie metabolismu analgetika flupirtinu in vitro (cs) Investigation of the in vitro metabolism of the analgesic flupirtine (en)
skos:prefLabel	Investigation of the in vitro metabolism of the analgesic flupirtine Studie metabolismu analgetika flupirtinu in vitro (cs) Investigation of the in vitro metabolism of the analgesic flupirtine (en)
skos:notation	RIV/68081707:_____/09:00322176!RIV09-AV0-68081707
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1QS500040581), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Vrána, Oldřich
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	320340
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/09:00322176
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	flupirtine; analgesic; metabolism (en)
http://linked.open.../riv/klicoveSlovo	metabolism analgesic flupirtine
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[68CEA5EA3248]
http://linked.open...i/riv/nazevZdroje	Drug Metabolism and Disposition
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Metallodrugs, design and mechansim of action
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	37
http://linked.open...iv/tvurceVysledku	Bednarski, P. J. Vrána, Oldřich Lalk, M. Methling, K. Reszka, P. Scheuch, E. Siegmund, W. Terhaag, B.
http://linked.open...ain/vavai/riv/wos	000263516500007
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	0090-9556
number of pages	15 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Investigation of the in vitro metabolism of the analgesic flupirtine Investigation of the in vitro metabolism of the analgesic flupirtine Investigation of the in vitro metabolism of the analgesic flupirtine Investigation of the in vitro metabolism of the analgesic flupirtine

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