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  • Analyses showed that H3K9 trimethylation, variants of HP1 proteins and centromeric heterochromatin are important markers how to distinguish between pluripotent and differentiated stages of human embryonic stem cells (hESCs). Conversely, except centromeres, nuclear radial distributions were conserved in pluripotent and differentiated hESCs.
  • Analyses showed that H3K9 trimethylation, variants of HP1 proteins and centromeric heterochromatin are important markers how to distinguish between pluripotent and differentiated stages of human embryonic stem cells (hESCs). Conversely, except centromeres, nuclear radial distributions were conserved in pluripotent and differentiated hESCs. (en)
  • Analýzy ukázaly, že H3K9 trimethylace, varianty HP1 proteinu a centromerický heterochromatin jsou důležité markery pro rozlišení mezi pluripotentním a diferencovaným stavem lidských embryonálních kmenových buněk (hESCs). Na druhou stranu, kromě centromer, radiální distribuce chromatinu jsou z velké části shodné jak u pluripotentních, tak diferencovaných hES buněk. (cs)
Title
  • Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation
  • Epigenom a struktura chromatinu u lidských embryonálních kmenových buněk stimulovaných k diferenciaci (cs)
  • Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation (en)
skos:prefLabel
  • Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation
  • Epigenom a struktura chromatinu u lidských embryonálních kmenových buněk stimulovaných k diferenciaci (cs)
  • Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation (en)
skos:notation
  • RIV/68081707:_____/08:00318537!RIV09-AV0-68081707
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1QS500040508), P(GA204/06/0978), P(LC535), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika
  • 12
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
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  • 366396
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/08:00318537
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • hESC; chromatin; histone modification (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [DE36A42EDDC6]
http://linked.open...i/riv/nazevZdroje
  • Developmental Dynamics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 237
http://linked.open...iv/tvurceVysledku
  • Bártová, Eva
  • Kozubek, Stanislav
  • Strašák, Luděk
  • Galiová, Gabriela
  • Kroupová, Jana
  • Harničarová, Andrea
http://linked.open...ain/vavai/riv/wos
  • 000261679300022
http://linked.open...n/vavai/riv/zamer
issn
  • 1058-8388
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