About: Quadruplexes of human telomere DNA

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Secondary structures of the G-rich strand of human telomere DNA fragments G3(TTAG3)n, n=1-16, have been studied by means of CD spectroscopy and polyacrylamide gel electrophoresis, in solutions of physiological potassium cation concentrations. It has been found that folding of these fragments into quadruplexes as well as quadruplex thermostabilities and enthalpy values depend on the number of TTAG3. Secondary structures of the G-rich strand of human telomere DNA fragments G3(TTAG3)n, n=1-16, have been studied by means of CD spectroscopy and polyacrylamide gel electrophoresis, in solutions of physiological potassium cation concentrations. It has been found that folding of these fragments into quadruplexes as well as quadruplex thermostabilities and enthalpy values depend on the number of TTAG3. (en) Pomocí CD spektroskopie a polyakrylamidové gelové elektroforézy jsme studovali sekundární strukturu G-bohatého řetězce lidské telomerní DNA G3(TTAG3)n, n=1-16 fragmentů, v prostředí o fyziologické koncentraci draselných iontů. Zjistili jsme, že skládání těchto fragmentů do kvadruplexů, termostabilita kvadruplexů a enthalpie závisejí na počtu TTAG3. (cs)
Title	Quadruplexes of human telomere DNA Kvadruplexy lidské telomerní DNA (cs) Quadruplexes of human telomere DNA (en)
skos:prefLabel	Quadruplexes of human telomere DNA Kvadruplexy lidské telomerní DNA (cs) Quadruplexes of human telomere DNA (en)
skos:notation	RIV/68081707:_____/07:00085928!RIV08-AV0-68081707
http://linked.open.../vavai/riv/strany	710
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA204/07/0057), P(IAA100040701), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Kypr, Jaroslav Vorlíčková, Michaela Chládková, Jana Kejnovská, Iva
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	446090
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/07:00085928
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA tetraplex; human telomere; CD spectroscopy (en)
http://linked.open.../riv/klicoveSlovo	CD spectroscopy human telomere DNA tetraplex
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[06314E24AF23]
http://linked.open...i/riv/nazevZdroje	Journal of Biomolecular Structure & Dynamics
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Biophysical Properties of Biologically and Medically Important Regions of Human DNA Tetraplexes in the human genome
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Kypr, Jaroslav Vorlíčková, Michaela Kejnovská, Iva Chládková, Jana
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	0739-1102
number of pages	1 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Quadruplexes of human telomere DNA Quadruplexes of human telomere DNA Quadruplexes of human telomere DNA

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