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| rdf:type
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| Description
| - Secondary structures of the G-rich strand of human telomere DNA fragments G3(TTAG3)n, n=1-16, have been studied by means of CD spectroscopy and polyacrylamide gel electrophoresis, in solutions of physiological potassium cation concentrations. It has been found that folding of these fragments into tetraplexes as well as tetraplex thermostabilities and enthalpy values depend on the number of TTAG3 repeats. The suggested topologies include, for example, antiparallel and parallel bimolecular tetraplexes, an intramolecular antiparallel tetraplex, a tetraplex consisting of three parallel chains and one antiparallel chain a poorly stable parallel intramolecular tetraplex, and both parallel and antiparallel tetramolecular tetraplexes. G3(TTAG3)3 folds into a single, stable, and very compact intramolecular antiparallel tetraplex.
- Secondary structures of the G-rich strand of human telomere DNA fragments G3(TTAG3)n, n=1-16, have been studied by means of CD spectroscopy and polyacrylamide gel electrophoresis, in solutions of physiological potassium cation concentrations. It has been found that folding of these fragments into tetraplexes as well as tetraplex thermostabilities and enthalpy values depend on the number of TTAG3 repeats. The suggested topologies include, for example, antiparallel and parallel bimolecular tetraplexes, an intramolecular antiparallel tetraplex, a tetraplex consisting of three parallel chains and one antiparallel chain a poorly stable parallel intramolecular tetraplex, and both parallel and antiparallel tetramolecular tetraplexes. G3(TTAG3)3 folds into a single, stable, and very compact intramolecular antiparallel tetraplex. (en)
- Pomocí cirkulárního dichroismu a PAGE byla studována uspořádání G-bohatých fragmentů lidské telomerní DNA, G3(TTAG3)n (n=1-16) v roztocích fyziologických koncentrací K+. Bylo zjištěno, že tyto fragmenty tvoří tetraplexy, jejichž topologie, termostabilita a entalpie jsou závislé na počtu opakování motivu TTAG3. Předpokládaná uspořádání zahrnují antiparalelní a paralelní bimolekulární tetraplexy, intramolekulární antiparalelní tetraplex, tetraplex sestávající se ze tří paralelních řetězců a jednoho antiparalelního řetězce, málo stabilní paralelní intramolekulární tetraplex a paralelní i antiparalelní tetramolekulární tetraplexy. G3(TTAG3)3 tvoří stabilní a velmi kompaktní intramolekulární antiparalelní tetraplex. (cs)
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| Title
| - Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats
- Topologie guaninových tetraplexů lidské telomérní DNA je řízena počtem opakování (TTAGGG) (cs)
- Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats (en)
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| skos:prefLabel
| - Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats
- Topologie guaninových tetraplexů lidské telomérní DNA je řízena počtem opakování (TTAGGG) (cs)
- Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats (en)
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| skos:notation
| - RIV/68081707:_____/05:00022150!RIV06-AV0-68081707
|
| http://linked.open.../vavai/riv/strany
| |
| http://linked.open...avai/riv/aktivita
| |
| http://linked.open...avai/riv/aktivity
| - P(IAA4004201), P(NM7634), Z(AV0Z50040507)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
| |
| http://linked.open...titaPredkladatele
| |
| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/68081707:_____/05:00022150
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - quadruplexes; human telomere; DNA conformational properties (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
| |
| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...vavai/riv/projekt
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Kypr, Jaroslav
- Vorlíčková, Michaela
- Kejnovská, Iva
- Fialová, Markéta
- Chládková, Jana
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| http://linked.open...n/vavai/riv/zamer
| |
| issn
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| number of pages
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| is http://linked.open...avai/riv/vysledek
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