About: DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair.

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About: DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The paper describes molecular mechanisms underlying antitumor activity of the novel PhaseII antitumor platinum drug BBR3464. The results indicate that the crucial role in these mechanisms is played by interstrand cross-links formed by this drug in DNA. The paper describes molecular mechanisms underlying antitumor activity of the novel PhaseII antitumor platinum drug BBR3464. The results indicate that the crucial role in these mechanisms is played by interstrand cross-links formed by this drug in DNA. (en)
Title	DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. (en)
skos:prefLabel	DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair. (en)
skos:notation	RIV/68081707:_____/02:17023143!RIV/2003/GA0/A17003/N
http://linked.open.../vavai/riv/strany	48076;48086
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/02/1552), P(IAA5004101), P(NL6058), Z(AV0Z5004920)
http://linked.open...iv/cisloPeriodika	50
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Brabec, Viktor Kašpárková, Jana Zehnulová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	643498
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/02:17023143
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	DNA; platinum; cancer (en)
http://linked.open.../riv/klicoveSlovo	DNA cancer platinum
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[75BE0ACD07D7]
http://linked.open...i/riv/nazevZdroje	Journal of Biological Chemistry
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Platinated oligonucleotides for selective modulation of gene expression; relations to antisense strategy and development of new drugs. Structure, recognition and biochemistry of DNA modified by antitumor platinum drugs Recognition and repair of DNA damage by antitumor platinum drugs.Relations to the development of new anticancer drugs.
http://linked.open...UplatneniVysledku	2002
http://linked.open...v/svazekPeriodika	277
http://linked.open...iv/tvurceVysledku	Brabec, Viktor Kašpárková, Jana Farrell, N. Zehnulová, Jana
http://linked.open...n/vavai/riv/zamer	Biophysical properties of living systems and their changes under the influence of environmental factors
issn	0021-9258
number of pages	11 (xsd:int)

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