About: Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat

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About: Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We found that the SHR. congenic strain carrying a segment of chromosome 2 from the BN rat had significantly lower systolic and diastolic blood pressures and cardiac mass than the SHR progenitor strain. These findings demonstrate that gene(s) with major effects on blood pressure and cardiac mass exist in the differential segment of chromosome 2 trapped within the new SHR.BN congenic strain We found that the SHR. congenic strain carrying a segment of chromosome 2 from the BN rat had significantly lower systolic and diastolic blood pressures and cardiac mass than the SHR progenitor strain. These findings demonstrate that gene(s) with major effects on blood pressure and cardiac mass exist in the differential segment of chromosome 2 trapped within the new SHR.BN congenic strain (en) Bylo zjištěno, že SHR kongenní kmen nesoucí úsek chromozomu 2 z kmene BN, má nižší systolický a diastolický krevní tlak a srdeční hmotnost. Tyto vyýsledky prokazují, že gen nebo geny s významnými účinky na krevní tlak a srdeční hmotnost byly geneticky izolovány v SHR.BN-chr.2 kongenním kmenu (cs)
Title	Genetická izolace lokusu kvantitativních znaků pro krevní tlak na chromozomu 2 u spontánně hypertenzních potkanů (cs) Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat (en)
skos:prefLabel	Genetická izolace lokusu kvantitativních znaků pro krevní tlak na chromozomu 2 u spontánně hypertenzních potkanů (cs) Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat (en)
skos:notation	RIV/67985823:_____/01:00142137!RIV07-AV0-67985823
http://linked.open.../vavai/riv/strany	1061;1064
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/00/1646), P(GV204/98/K015), P(LN00A079), Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2007
http://linked.open...aciTvurceVysledku	Musilová, Alena Zídek, Václav Pravenec, Michal Vorlíček, Jaroslav Křen, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	681060
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/01:00142137
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	spontaneously hypertensive rat; congenic; chromosome 2 (en)
http://linked.open.../riv/klicoveSlovo	spontaneously hypertensive rat chromosome 2 congenic
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[6CFB68F324FA]
http://linked.open...i/riv/nazevZdroje	Journal of Hypertension
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Molecular mapping and positional cloning of genes that are responsible for clustering of cardiovascular risk factors Center of Integrated Genomics Molecular mapping of the mammalian genome and positional cloning of mammalian genes
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	19
http://linked.open...iv/tvurceVysledku	Křen, Vladimír Pravenec, Michal Vorlíček, Jaroslav Zídek, Václav Musilová, Alena Kurtz, W. T. St. Lezin, E.
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0263-6352
number of pages	4 (xsd:int)

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