About: Derivatives 2-phenyl-3-hydroxyquinoline-4(1H)-ones and methods of their preparation and utilization

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Patent is protected the preparation and utlization of derivatives of 2-phenyl-3-hydroxyquinolin-4(1H)-ones having nitro and substituted aminogroup in phenyl in position 2 as compounds with anticancer activity. These compounds exhibit micromolar values of IC50 against drug-sensitive as well as drug-resistant cancer cell lines. Patent is protected the preparation and utlization of derivatives of 2-phenyl-3-hydroxyquinolin-4(1H)-ones having nitro and substituted aminogroup in phenyl in position 2 as compounds with anticancer activity. These compounds exhibit micromolar values of IC50 against drug-sensitive as well as drug-resistant cancer cell lines. (en)
Title	Derivatives 2-phenyl-3-hydroxyquinoline-4(1H)-ones and methods of their preparation and utilization Derivatives 2-phenyl-3-hydroxyquinoline-4(1H)-ones and methods of their preparation and utilization (en)
skos:prefLabel	Derivatives 2-phenyl-3-hydroxyquinoline-4(1H)-ones and methods of their preparation and utilization Derivatives 2-phenyl-3-hydroxyquinoline-4(1H)-ones and methods of their preparation and utilization (en)
skos:notation	RIV/61989592:15310/12:33141483!RIV13-MSM-15310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(ED0030/01/01), P(TE01020028)
http://linked.open...cisloPatentuVzoru	US8299092 B2
http://linked.open...eleniPatentuVzoru	2012-10-30 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Hlaváč, Jan Hradil, Pavel Krejčí, Petr
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	130186
http://linked.open...ai/riv/idVysledku	RIV/61989592:15310/12:33141483
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	quinoline, anticancer,; preparation; methods; 2-phenyl-3-hydroxyquinoline-41H-ones; Derivatives (en)
http://linked.open.../riv/klicoveSlovo	Derivatives quinoline methods 2-phenyl-3-hydroxyquinoline-41H-ones anticancer preparation
http://linked.open...ontrolniKodProRIV	[B6E6CB9DD2D4]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	Alexandria
http://linked.open...atelePatentuVzoru	United States Patent and Trademark Office (USPTO)
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Biomedicine for regional development and human resources Center for Development of Original Drugs
http://linked.open...UplatneniVysledku	2012
http://linked.open...ydaniPatentuVzoru	US - Spojené státy americké
http://linked.open...iv/tvurceVysledku	Hajdúch, Marián Hlaváč, Jan Hradil, Pavel Krejčí, Petr
http://linked.open...mniOchranaPatentu	B - USTPO (Úřad pro patenty a ochranné známky USA)
http://linked.open...avai/riv/vlastnik	Univerzita Palackého v Olomouci
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	A - Pouze udělený nebo využívaný pouze vlastníkem
http://linked.open...stnikPatentuVzoru	Univerzita Palackého v Olomouci
http://localhost/t...ganizacniJednotka	15310

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