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  • a-D-Galactosidases (a-D-galactoside galactohydrolase, E.C. 3.2.1.22) are exoglycosidases, which in vivo catalyze the hydrolysis of simple and complex oligo- and polysaccharides containing terminal a-D-galactosyl groups. A number of industrial applications of a-D- galactosidases are known, mainly in the sugar industry, pulp and paper industry or medicine. Although a-D-galactosidases occur in all living systems, microbial and possibly plant enzymes are preferred for practical applications. The regioselectivity of glycosidases is somewhat poor. Selective protection of oligosaccharides and development of new modified donors/acceptors is a promising method to overcome this problem. Genetic engineering has enabled the creation of glycosynthases from the hydrolytic glycosidases, which are highly complementary to glycosyltransferases. The present review summarizes recent advances in the application of a-D-galactosidases in synthetic and biotransformation applications
  • a-D-Galactosidases (a-D-galactoside galactohydrolase, E.C. 3.2.1.22) are exoglycosidases, which in vivo catalyze the hydrolysis of simple and complex oligo- and polysaccharides containing terminal a-D-galactosyl groups. A number of industrial applications of a-D- galactosidases are known, mainly in the sugar industry, pulp and paper industry or medicine. Although a-D-galactosidases occur in all living systems, microbial and possibly plant enzymes are preferred for practical applications. The regioselectivity of glycosidases is somewhat poor. Selective protection of oligosaccharides and development of new modified donors/acceptors is a promising method to overcome this problem. Genetic engineering has enabled the creation of glycosynthases from the hydrolytic glycosidases, which are highly complementary to glycosyltransferases. The present review summarizes recent advances in the application of a-D-galactosidases in synthetic and biotransformation applications (en)
Title
  • Alfa-Galactosidases and their applications in biotransformations
  • Alfa-Galactosidases and their applications in biotransformations (en)
skos:prefLabel
  • Alfa-Galactosidases and their applications in biotransformations
  • Alfa-Galactosidases and their applications in biotransformations (en)
skos:notation
  • RIV/61388971:_____/09:00327476!RIV10-MSM-61388971
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA203/05/0172), P(LC06010), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 302431
http://linked.open...ai/riv/idVysledku
  • RIV/61388971:_____/09:00327476
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • -Galactosidase; enzyme; transglycosylation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [42E75652A5CE]
http://linked.open...i/riv/nazevZdroje
  • Biocatalysis and Biotransformation
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 27
http://linked.open...iv/tvurceVysledku
  • Křen, Vladimír
  • Weignerová, Lenka
  • Simerská, Pavla
http://linked.open...ain/vavai/riv/wos
  • 000263717000001
http://linked.open...n/vavai/riv/zamer
issn
  • 1024-2422
number of pages
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