About: Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo

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About: Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Srovnání schopností tří nově vyvinutých oximů jako reaktivátorů AcHE. (cs) Reactivation potency of three newly developed oximes K027, K033 and K048 was tested using standard in vitro and in vivo reactivation tests. K027 and K048 seem to be efficacious reactivators of tabun-inhibited acetylcholinesterase. K033 is sufficient reactivator of cyclosarin-inhibited AChE. However, its potency is poor compared with current %22gold standard%22 oxime HI-6. Reactivation potency of three newly developed oximes K027, K033 and K048 was tested using standard in vitro and in vivo reactivation tests. K027 and K048 seem to be efficacious reactivators of tabun-inhibited acetylcholinesterase. K033 is sufficient reactivator of cyclosarin-inhibited AChE. However, its potency is poor compared with current %22gold standard%22 oxime HI-6. (en)
Title	Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo (en) Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo (cs)
skos:prefLabel	Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo (en) Comparison of the potency of newly developed and currently available oximes to reactivate nerve agent-inhibited acetylcholinesterase in vitro and in vivo (cs)
skos:notation	RIV/60162694:G44__/05:00001304!RIV06-MO0-G44_____
http://linked.open.../vavai/riv/strany	367-368
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(OBVLAJEP20032), P(ONVLAJEP20031)
http://linked.open...iv/cisloPeriodika	157-158
http://linked.open...vai/riv/dodaniDat	2006
http://linked.open...aciTvurceVysledku	Bartošová, Lucie Cabal, Jiří Jun, Daniel Kassa, Jiří Kuča, Kamil Bajgar, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	515926
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/05:00001304
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Acetylcholinesterase; Reactivator; Oxime; Tabun; Cyclosarin (en)
http://linked.open.../riv/klicoveSlovo	Tabun Acetylcholinesterase Reactivator Oxime Cyclosarin
http://linked.open...odStatuVydavatele	IE - Irsko
http://linked.open...ontrolniKodProRIV	[1CA8F43E6C83]
http://linked.open...i/riv/nazevZdroje	Chemico-Biological Interactions
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	New possibilities of therapy of cyclosin intoxication: Synthesis and testing of new acethylcholinesterase reactivators C-AGENTS - Medical problem of human being, animal andplant protection against topical types of military useable chemical agents
http://linked.open...UplatneniVysledku	2005
http://linked.open...v/svazekPeriodika	3
http://linked.open...iv/tvurceVysledku	Bajgar, Jiří Cabal, Jiří Kassa, Jiří Kuča, Kamil Jun, Daniel Bartošová, Lucie Kunešová, Gabriela
issn	0009-2797
number of pages	2 (xsd:int)
http://localhost/t...ganizacniJednotka	G44

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