About: Chromocentre integrity and epigenetic marks

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The epigenetic modification of histones dictates the formation of euchromatin and heterochromatin domains. We studied the effects of a deficiency of histone methyltransferase, SUV39h, and trichostatin A-dependent hyperacetylation on the structural stability of centromeric clusters, called chromocentres. We did not observe the expected disintegration of chromocentres, but both SUV39h deficiency and hyperacetylation in SUV39h+/+ cells induced the re-positioning of chromocentres closer to the nuclear periphery. The epigenetic modification of histones dictates the formation of euchromatin and heterochromatin domains. We studied the effects of a deficiency of histone methyltransferase, SUV39h, and trichostatin A-dependent hyperacetylation on the structural stability of centromeric clusters, called chromocentres. We did not observe the expected disintegration of chromocentres, but both SUV39h deficiency and hyperacetylation in SUV39h+/+ cells induced the re-positioning of chromocentres closer to the nuclear periphery. (en)
Title	Chromocentre integrity and epigenetic marks Chromocentre integrity and epigenetic marks (en)
skos:prefLabel	Chromocentre integrity and epigenetic marks Chromocentre integrity and epigenetic marks (en)
skos:notation	RIV/00216224:14330/10:00051222!RIV12-MSM-14330___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LC06027), P(LC535), P(ME 919), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Matula, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Fakulta informatiky
http://linked.open...dnocenehoVysledku	250710
http://linked.open...ai/riv/idVysledku	RIV/00216224:14330/10:00051222
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	SUV39h; epigenetics; histone methylation (en)
http://linked.open.../riv/klicoveSlovo	SUV39h epigenetics histone methylation
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[B757E9C243A8]
http://linked.open...i/riv/nazevZdroje	Journal of Structural Biology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Chromosome dynamics and organization during the cell cycle in normal and pathologic conditions University Research Centre - Czech Myeloma Group http://linked.opendata.cz/resource/domain/vavai/projekt/ME%20919
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	169
http://linked.open...iv/tvurceVysledku	Bártová, Eva Kozubek, Stanislav Matula, Pavel Legartová, Soňa Galiová, Gabriela Harničarová, Andrea
http://linked.open...ain/vavai/riv/wos	000274043100015
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	1047-8477
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.jsb.2009.09.007
http://localhost/t...ganizacniJednotka	14330
is http://linked.open...avai/riv/vysledek of	Chromocentre integrity and epigenetic marks Chromocentre integrity and epigenetic marks

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