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rdf:type
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rdfs:seeAlso
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Description
| - In this study, the complexation rates of two new phosphinate H(4)dota (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) analogs, H(5)do3ap(PrA) and H(4)do3ap(ABn), and H(4)dota itself were compared under identical conditions (H(5)do3ap(PrA) = 10-([(2-carboxyethyl) hydroxyphosphoryl]methyl) -1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid; H(4)do3ap(ABn) = 10-{[(4-aminophenyl) hydroxyphosphoryl]methyl}-1,4.7,10-tetraazacyclododecane-1,4,7-triacetic acid). The biodistribution of their (111)In and (90)Y complexes in healthy rats was also studied. Unlike the observation obtained under %22chemical%22 conditions where differences between the ligands were observed no such differences in complexation rates were found under radiochemical conditions. The ligands bind the radiometals similarly to H(4)dota. So, %22chemical%22 formation kinetic data should be transferred into radiochemical conditions only with high care and %22radiochemical%22 complexation experiments should be run a
- In this study, the complexation rates of two new phosphinate H(4)dota (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) analogs, H(5)do3ap(PrA) and H(4)do3ap(ABn), and H(4)dota itself were compared under identical conditions (H(5)do3ap(PrA) = 10-([(2-carboxyethyl) hydroxyphosphoryl]methyl) -1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid; H(4)do3ap(ABn) = 10-{[(4-aminophenyl) hydroxyphosphoryl]methyl}-1,4.7,10-tetraazacyclododecane-1,4,7-triacetic acid). The biodistribution of their (111)In and (90)Y complexes in healthy rats was also studied. Unlike the observation obtained under %22chemical%22 conditions where differences between the ligands were observed no such differences in complexation rates were found under radiochemical conditions. The ligands bind the radiometals similarly to H(4)dota. So, %22chemical%22 formation kinetic data should be transferred into radiochemical conditions only with high care and %22radiochemical%22 complexation experiments should be run a (en)
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Title
| - Complexation and biodistribution study of (111)In and (90)Y complexes of bifunctional phosphinic acid analogs of H(4)dota
- Complexation and biodistribution study of (111)In and (90)Y complexes of bifunctional phosphinic acid analogs of H(4)dota (en)
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skos:prefLabel
| - Complexation and biodistribution study of (111)In and (90)Y complexes of bifunctional phosphinic acid analogs of H(4)dota
- Complexation and biodistribution study of (111)In and (90)Y complexes of bifunctional phosphinic acid analogs of H(4)dota (en)
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skos:notation
| - RIV/00216208:11120/09:00003097!RIV12-MSM-11120___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1QS100480501), P(GA203/06/0467), P(GA305/07/0535), P(KAN201110651), P(OC 179), P(OC08006), S, V, Z(AV0Z10480505), Z(MSM0021620857)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/09:00003097
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Biodistribution; Cyclen derivatives; DOTA; Indium complexes; Macrocycles; Nuclear medicine; Phosphinate complexes; Radiopharmaceuticals; Yttrium complexes (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Applied Radiation and Isotopes
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Melichar, František
- Försterová, Michaela
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.apradiso.2008.08.013
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http://localhost/t...ganizacniJednotka
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is http://linked.open...avai/riv/vysledek
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