About: New analytical approaches for identification of proteins with significant attributes for virulence and pathogenity of bacteria

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: New analytical approaches for identification of proteins with significant attributes for virulence and pathogenity of bacteria Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=GA203/09/0857
Description	The project aims at the innovative analytical approach based on biofunctionalized magnetic micro/nanoparticles combined with microfluidic analytical device (m-TAS). Benefits provided by both systems open the feasibility to use this microanalyzator for effective separation of bacterial proteins from highly complex mixture. The analyses will be focused on significant attributes of virulence and pathogenesis within intracellular parasite. New analytical strategy combined with mass spectrometry (MS) enables to isolate and characterize the structure of low-abundant glykoproteins, phosphoproteins and in other way modified proteins from cell lysate or membrane fractions of bacteria and identify biomolecules predicting the virulence of bacteria strains. The immobilized magnetic affinity reactor (IMAR) with specific ligand used for isolation and purification of proteins significantly facilitates the identification of protein fingerprint by MS even for bacterial protein in submicromolar concentration. Comparative analyses will be performed on the target proteins isolated from two bacterial strains of Francisella tularensis differing in virulence. (en) Vyvinout a validovat mikroprůtokový analytický systém, jehož integrální součástí jsou specifickým ligandem modifikované magnetické mikro/nanočástice; tento systém použít k identifikaci a strukturní charakterizaci bakteriálních proteinů majících vztah k virulenci a patogenezi bakterií.
Title	New analytical approaches for identification of proteins with significant attributes for virulence and pathogenity of bacteria (en) Nové analytické postupy k identifikaci proteinů spjatých s virulencí a patogenezí bakteriálních kmenů
skos:notation	GA203/09/0857
http://linked.open...avai/cep/aktivita	Standard projects
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/GA203%2F09%2F0857/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/GA203%2F09%2F0857/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2015-03-02 (xsd:date)
http://linked.open...i/cep/druhSouteze	VS - Veřejná soutěž ve výzkumu a vývoji
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	91492610
http://linked.open...ai/cep/hlavniObor	CB - Analytická chemie, separace
http://linked.open...hodnoceniProjektu	V - Vynikající výsledky (s mezinárodním významem apod.). Zároveň byly splněny cíle a předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory.
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	bioafinitní chromatografie, magnetické částice, mikrofluidní systém, proteiny, bakterie, hmotnostní (en)
http://linked.open...ep/partnetrHlavni	Fakulta chemicko-technologická
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	3 (xsd:int)
http://linked.open.../pocetVysledkuRIV	22 (xsd:int)
http://linked.open...enychVysledkuVRIV	22 (xsd:int)
http://linked.open...lneniVMinulemRoce	2011-04-16 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/203%2F09%2F0857
http://linked.open...iciPoslednihoRoku	2011
http://linked.open...atUdajeProjZameru	2012
http://linked.open.../vavai/cep/soutez	SGA02009GA-ST
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2011-12-31 (xsd:date)
http://linked.open.../cep/vedlejsiObor	EE - Mikrobiologie, virologie
http://linked.open...ep/zahajeniReseni	2009-01-01 (xsd:date)
http://linked.open...jektu+dodavatelem	Řešení projektu proběhlo výtečně, jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs) The project was excellent, both in terms of expertise and in terms of disbursement of funds. (en)
http://linked.open...tniCyklusProjektu	ZBKU
http://linked.open.../cep/klicoveSlovo	bakterie magnetické částice mikrofluidní systém proteiny bioafinitní chromatografie
is http://linked.open...vavai/riv/projekt of	Peptidové inhibitory imobilizované na magnetické nosiče a Sepharosu aplikované na separaci žaludečních aspartátových proteinas Laccase immobilized on magnetic carriers for biotechnology applications Multimethodological approach to identification of glycoproteins from the proteome of Francisella tularensis an intracellular microorganism %22Sladký%22 svět bakterií: metodické přístupy využívané v analýze bakteriálních glykoproteinů Magnetic poly(glycidyl methacrylate) particles prepared in the presence of surface-modified .gamma.-Fe2O3 Monodisperse magnetic composite poly(glycidyl methacrylate)/La0.75Sr0.25MnO3 microspheres by the dispersion polymerization Semisynthesis of C17:0 isoforms of sulphatide and glucosylceramide using immobilised sphingolipid ceramide N-deacylase for application in analytical mass spectrometry Streptavidin-modified magnetic poly(2-hydroxyethyl methacrylate-co-glycidyl methacrylate) microspheres for selective isolation of bacterial DNA Utilization of immobilized lysozyme for identification of bacterial proteins by mass spectrometry Albumin-coated monodisperse magnetic poly(glycidyl methacrylate) microspheres with immobilized antibodies: Application to the capture of epithelial cancer cells Methods used for the analysis of bacteria Francisella tularensis phosphoproteins Iminodiacetic acid-modified magnetic poly(2-hydroxyethyl methacrylate) - based microspheres for phosphopeptide enrichment Size exclusion chromatography as a tool for evaluation of fragmentation pattern of gastric mucins under non-degrading conditions Characterization of Protein Glycosylation in Francisella tularensis subsp. holarctica Magnetic Bead Cellulose as a Suitable Support for Immobilization of alpha-Chymotrypsin Bioanalytical tools for the discovery of eukaryotic glycoproteins applied to the analysis of bacterial glycoproteins Microfluidic system with integrated magnetic carrier for immunoprecipitation of Aβ peptides. Phosphoprotein electrophoresis in the presence of Fe(III) ions Use of magnetic hydrazide-modified polymer microspheres for enrichment of Francisella tularensis glycoproteins Hypercrosslinked polystyrene microspheres by suspension and dispersion polymerization Immunomagnetic sulfonated hypercrosslinked polystyrene microspheres for electrochemical detection of proteins New monodisperse magnetic polymer microspheres biofunctionalized for enzyme catalysis and bioaffinity separations.
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2009/ico%3A61389013 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2009/orjk%3A11110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2009/orjk%3A25310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2009/orjk%3AG44 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2010/ico%3A61389013 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2010/orjk%3A11110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2010/orjk%3A25310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2010/orjk%3AG44 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2011/ico%3A61389013 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2011/orjk%3A11110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2011/orjk%3A25310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2011/orjk%3AG44 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2012/ico%3A61389013 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2012/orjk%3A11110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2012/orjk%3A25310 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA203%2F09%2F0857/2012/orjk%3AG44

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 112 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software