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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Naltrexone
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Naltrexone
UMLS_CUI
  • C0027360
CAS_Registry
  • 16590-41-3
FDA_UNII_Code
  • 5S6W795CQM
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that blocks the action of opiates (drugs used to treat pain). It may be used in the treatment of intravenous opiate addiction or alcohol dependence. Naltrexone is also being studied in the treatment of breast cancer. It may block the effects of the hormone estrogen, which causes some breast cancer cells to grow, or block the blood flow to tumors. It is a type of opiate antagonist.NCI-GLOSS
Chemical_Formula
  • C20H23NO4
Legacy_Concept_Name
  • Naltrexone_Base
CHEBI_ID
  • CHEBI:7465
FULL_SYN
  • naltrexonePTNCI-GLOSSCDR0000528022
  • NaltrexonePTDCP00452
  • NALTREXONEPTFDA5S6W795CQM
  • VivitrolPTNCI-GLOSSCDR0000549339
  • VivitrolBRNCI
  • NaltrexonePTNCI
DEFINITION
  • A noroxymorphone derivative with competitive opioid antagonistic property. Naltrexone reverses the effects of opioid analgesics by binding to the various opioid receptors in the central nervous system, including the mu-, kappa- and gamma-opioid receptors. This leads to an inhibition of the typical actions of opioid analgesics, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. Naltrexone is longer-acting and more potent compared to naloxone.NCI
code
  • C62055
sameAs
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