About: Levofloxacin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Levofloxacin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Levofloxacin
UMLS_CUI
  • C0282386
CAS_Registry
  • 138199-71-0
FDA_UNII_Code
  • 6GNT3Y5LMF
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance used to treat bacterial infections. It belongs to the family of drugs called quinolone antibiotics.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 37941
PDQ_Closed_Trial_Search_ID
  • 37941
Chemical_Formula
  • 2C18H20FN3O4.H2O
Legacy_Concept_Name
  • Levofloxacin
FULL_SYN
  • LEVOFLOXACINPTFDA6GNT3Y5LMF
  • LevofloxacinPTNCI
  • levofloxacinPTNCI-GLOSSCDR0000044906
  • QuixinBRNCI
  • LevaquinBRNCI
DEFINITION
  • A broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.NCI
code
  • C1586
sameAs
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