About: The antifungal effect of peptides from hymenoptera venom and their analogs

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Minimal inhibitory concentrations (MICs) against different Candida species (C. albicans, C. krusei, C. glabrata, C. tropicalis and C. parapsilosis) of recently isolated, synthesized and characterized antimicrobial alpha-helical amphipathic peptides (12–18 amino acids long) from the venom of hymenoptera (melectin, lasioglossins I, II, and III, halictines I and II) as well as a whole series of synthetic analogs were determined. In the case of the natural peptides they amounted to 4–20 .mu.M (7–40 mg/l). The most active ones were the synthetic analogs all-D-lasioglossin III and KNWKK-Aib-LGK-Aib-IK-Aib-VK-NH2. Minimal inhibitory concentrations (MICs) against different Candida species (C. albicans, C. krusei, C. glabrata, C. tropicalis and C. parapsilosis) of recently isolated, synthesized and characterized antimicrobial alpha-helical amphipathic peptides (12–18 amino acids long) from the venom of hymenoptera (melectin, lasioglossins I, II, and III, halictines I and II) as well as a whole series of synthetic analogs were determined. In the case of the natural peptides they amounted to 4–20 .mu.M (7–40 mg/l). The most active ones were the synthetic analogs all-D-lasioglossin III and KNWKK-Aib-LGK-Aib-IK-Aib-VK-NH2. (en)
Title	The antifungal effect of peptides from hymenoptera venom and their analogs The antifungal effect of peptides from hymenoptera venom and their analogs (en)
skos:prefLabel	The antifungal effect of peptides from hymenoptera venom and their analogs The antifungal effect of peptides from hymenoptera venom and their analogs (en)
skos:notation	RIV/61388963:_____/11:00360967!RIV12-AV0-61388963
http://linked.open...avai/predkladatel	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(GA203/08/0536), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Monincová, Lenka Slaninová, Jiřina Fučík, Vladimír Putnová, Helena Borovičková, Lenka Čeřovský, Václav Šácha, Pavel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	186444
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/11:00360967
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	antifungal agents; candida; fluorescent microscopy; rhodamine 6G; fluorescein-labeled peptide (en)
http://linked.open.../riv/klicoveSlovo	antifungal agents candida fluorescein-labeled peptide fluorescent microscopy rhodamine 6G
http://linked.open...odStatuVydavatele	PL - Polská republika
http://linked.open...ontrolniKodProRIV	[5D69E3D94255]
http://linked.open...i/riv/nazevZdroje	Central European Journal of Biology
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Antimicrobial peptides from insects for possible therapeutic applications
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	6
http://linked.open...iv/tvurceVysledku	Borovičková, Lenka Fučík, Vladimír Monincová, Lenka Putnová, Helena Slaninová, Jiřina Čeřovský, Václav Šácha, Pavel
http://linked.open...ain/vavai/riv/wos	000287457200003
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	1895-104X
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.2478/s11535-010-0111-4
is http://linked.open...avai/riv/vysledek of	The antifungal effect of peptides from hymenoptera venom and their analogs The antifungal effect of peptides from hymenoptera venom and their analogs

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