About: Metabolism of bromide and its interference with the metabolism of iodine

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The present knowledge about the metabolism of bromide with respect to its goitrogenic effects, including some conclusions drawn from our recent research on this subject, is reviewed. It is suggested that high levels of bromide in the organism of experimental animals can influence their iodine metabolism in two parallel ways: by a decrease in iodide accumulation in the thyroid and skin (and in the mammary glands in lactating dams), and by a rise in iodide excretion by kidneys. The present knowledge about the metabolism of bromide with respect to its goitrogenic effects, including some conclusions drawn from our recent research on this subject, is reviewed. It is suggested that high levels of bromide in the organism of experimental animals can influence their iodine metabolism in two parallel ways: by a decrease in iodide accumulation in the thyroid and skin (and in the mammary glands in lactating dams), and by a rise in iodide excretion by kidneys. (en) V práci je podán přehled současných poznatků o metabolismu bromidu ve vztahu k jeho strumigenním účinkům, včetně některých závěrů plynoucích z výsledků našeho nedávného výzkumu této problematiky. Naznačujeme, že vysoké hladiny bromidu v organismu experimentálních zvířat mohou ovlivňovat jejich metabolismus jodu dvěma paralelními způsoby: snížením akumulace jodidu ve štítné žláze a v kůži (a v mléčných žlázách v případě laktujících samic), a zvýšením vylučování jodidu ledvinami. (cs)
Title	Metabolism of bromide and its interference with the metabolism of iodine Metabolism of bromide and its interference with the metabolism of iodine (en) Metabolismus bromidu a jeho interference s metabolismem jodu (cs)
skos:prefLabel	Metabolism of bromide and its interference with the metabolism of iodine Metabolism of bromide and its interference with the metabolism of iodine (en) Metabolismus bromidu a jeho interference s metabolismem jodu (cs)
skos:notation	RIV/00216224:14310/04:00019261!RIV09-AV0-14310___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z5011922)
http://linked.open...iv/cisloPeriodika	(Suppl. 1)
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Pavelka, Stanislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	573023
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/04:00019261
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Bromide; iodide; metabolism; rat; thyroid (en)
http://linked.open.../riv/klicoveSlovo	iodide Bromide metabolism rat thyroid
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[A17D36651125]
http://linked.open...i/riv/nazevZdroje	Physiological Research [IF=1.140 (2003); SCI #cit.<6>]
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	1 (xsd:int)
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Pavelka, Stanislav
http://linked.open...n/vavai/riv/zamer	Investigation of normal and pathological physiology of animals - the clarification of the physiological mechanisms operating in humans in health and disease
issn	0862-8408
number of pages	10 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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