About: Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this study, we genetically isolated and analyzed the genes within the salt sensitivity and hypertension QTLs on spontaneously hypertensive rat (SHR) SHR chromosome 18, by developing and characterising a series of congenic strains in which we transferred the corresponding region of chromosome 18 from the normotensive and salt resistant Brown Norway (BN) rat onto the genetic background of the salt sensitive SHR/Ola strain In this study, we genetically isolated and analyzed the genes within the salt sensitivity and hypertension QTLs on spontaneously hypertensive rat (SHR) SHR chromosome 18, by developing and characterising a series of congenic strains in which we transferred the corresponding region of chromosome 18 from the normotensive and salt resistant Brown Norway (BN) rat onto the genetic background of the salt sensitive SHR/Ola strain (en)
Title	Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat (en)
skos:prefLabel	Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat (en)
skos:notation	RIV/67985823:_____/09:00329310!RIV10-MSM-67985823
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0520), P(1P05ME791), P(GA301/08/0166), P(NR9388), Z(AV0Z50110509), Z(MSM0021620807)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Musilová, Alena Zídek, Václav Mlejnek, Petr Šimáková, Miroslava Pravenec, Michal Vorlíček, Jaroslav Křen, Vladimír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fyziologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	310788
http://linked.open...ai/riv/idVysledku	RIV/67985823:_____/09:00329310
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	spontaneously hypertensive rat; salt sensitivity; gene (en)
http://linked.open.../riv/klicoveSlovo	spontaneously hypertensive rat gene salt sensitivity
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[C6CBCF2535BD]
http://linked.open...i/riv/nazevZdroje	Hypertension
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	19 (xsd:int)
http://linked.open...vavai/riv/projekt	Positional cloning of a gene on chromosome 10 that is responsible for hypertension and metabolic defects in the spontaneously hypertensive rat Genetic analysis of the role of mitochondria in the pathogenesis of metabolic syndrome studied in new rat conplastic strains The nature of acute and chronic humoral renal graft rejection at the level of molecular biology Center for Applied Genomics
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	54
http://linked.open...iv/tvurceVysledku	Křen, Vladimír Kurtz, T. W. Mlejnek, Petr Pravenec, Michal Seidman, Ch. E. Wang, J. Vorlíček, Jaroslav Zídek, Václav Šimáková, Miroslava Aitman, T. J. Musilová, Alena Johnson, M. D. He, L. Vyklický, O. Wallace, C. A. Herman, D. Qi, N. R. Seidman, J. Wakimoto, H.
http://linked.open...ain/vavai/riv/wos	000269089100037
http://linked.open...n/vavai/riv/zamer	Metabolické, endokrinní a genetické aspekty prevence, diagnostiky a terapie kardiovaskulárních, cerebrovaskulárních a renovaskulárních onemocnění Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka
issn	0194-911X
number of pages	7 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat Dissection of Chromosome 18 Blood Pressure and Salt-Sensitivity Quantitative Trait Loci in the Spontaneously Hypertensive Rat

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