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  • We demonstrate the polymer (PHEG-PEG 5000,PHPMA)-bound drugs non targeted or targeted with monoclonal antibodies,do not induce expression of FasL on selected cencer cells,the pre-treatment with PHPMA-bound mobilizes the defense mechanisms of the tumor-bearing host,the treatment with selected monoclonal antibody-targeted PHPMA-bound DOX generates prolonged systemic antitumor immunity.
  • We demonstrate the polymer (PHEG-PEG 5000,PHPMA)-bound drugs non targeted or targeted with monoclonal antibodies,do not induce expression of FasL on selected cencer cells,the pre-treatment with PHPMA-bound mobilizes the defense mechanisms of the tumor-bearing host,the treatment with selected monoclonal antibody-targeted PHPMA-bound DOX generates prolonged systemic antitumor immunity. (en)
Title
  • Drug targeting in cancer therapy.
  • Drug targeting in cancer therapy. (en)
skos:prefLabel
  • Drug targeting in cancer therapy.
  • Drug targeting in cancer therapy. (en)
skos:notation
  • RIV/61388971:_____/00:53010014!RIV/2003/AV0/A53003/N
http://linked.open.../vavai/riv/strany
  • 35;40
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GV307/96/K226), P(NC5050), Z(AV0Z4050913), Z(AV0Z5020903)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
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http://linked.open...dnocenehoVysledku
  • 709199
http://linked.open...ai/riv/idVysledku
  • RIV/61388971:_____/00:53010014
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • monoclonal antibodies; - antitumor immunity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [F9C03BA199F4]
http://linked.open...v/mistoKonaniAkce
  • Chiang Mai [TH]
http://linked.open...i/riv/mistoVydani
  • Chiang Mai
http://linked.open...i/riv/nazevZdroje
  • Takeo Wada Cancer Research Symposium.
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
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http://linked.open...iv/tvurceVysledku
  • Kovář, Marek
  • Strohalm, Jiří
  • Ulbrich, Karel
  • Říhová, Blanka
  • Šírová, Milada
  • Jelínková, Markéta
  • Hovorka, Ondřej
  • Plocová, Daniela
  • Šťastný, Marek
  • Hoste, K.
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
number of pages
http://purl.org/ne...btex#hasPublisher
  • Chiang Mai University
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