About: Quantification of Acetaldehyde Released by Lung Cancer Cells in vintro Using Selected Ion Flow Tube Mass Spectrometry.

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The production of volatile compounds from cancer cell lines in vitro has been investigated using selected ion flow tube mass spectrometry (SIFT-MS). This technique enables on-line quantitative analyses of the headspace above cell/medium cultures. This paper reports the discovery that acetaldehyde is released by the lung cancer cell lines SK-MES and CALU-1. The concentration of acetaldehyde in the headspace of the medium/cell culture was measured after 16h incubation at 37degreesC and found to be proportional to the number of cancer cells in the medium (typically 10(8)). From these data, the acetaldehyde production rates of the SK-MES cells and the CALU-1 cells in vitro are determined to be 1 x 10(6) and 1.5-3 x 10(6) molecules/cell/min, respectively. The potential value of this new technique in cell biology and in industrial cell biotechnology is discussed. The production of volatile compounds from cancer cell lines in vitro has been investigated using selected ion flow tube mass spectrometry (SIFT-MS). This technique enables on-line quantitative analyses of the headspace above cell/medium cultures. This paper reports the discovery that acetaldehyde is released by the lung cancer cell lines SK-MES and CALU-1. The concentration of acetaldehyde in the headspace of the medium/cell culture was measured after 16h incubation at 37degreesC and found to be proportional to the number of cancer cells in the medium (typically 10(8)). From these data, the acetaldehyde production rates of the SK-MES cells and the CALU-1 cells in vitro are determined to be 1 x 10(6) and 1.5-3 x 10(6) molecules/cell/min, respectively. The potential value of this new technique in cell biology and in industrial cell biotechnology is discussed. (en)
Title	Quantification of Acetaldehyde Released by Lung Cancer Cells in vintro Using Selected Ion Flow Tube Mass Spectrometry. Quantification of Acetaldehyde Released by Lung Cancer Cells in vintro Using Selected Ion Flow Tube Mass Spectrometry. (en)
skos:prefLabel	Quantification of Acetaldehyde Released by Lung Cancer Cells in vintro Using Selected Ion Flow Tube Mass Spectrometry. Quantification of Acetaldehyde Released by Lung Cancer Cells in vintro Using Selected Ion Flow Tube Mass Spectrometry. (en)
skos:notation	RIV/61388955:_____/03:54030040!RIV/2004/AV0/A54004/N
http://linked.open.../vavai/riv/strany	845;850
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA202/03/0827), P(GA203/02/0737), Z(AV0Z4040901)
http://linked.open...iv/cisloPeriodika	N/A
http://linked.open...vai/riv/dodaniDat	2004
http://linked.open...aciTvurceVysledku	Španěl, Patrik
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav fyzikální chemie J. Heyrovského AV ČR, v.v.i.
http://linked.open...dnocenehoVysledku	624373
http://linked.open...ai/riv/idVysledku	RIV/61388955:_____/03:54030040
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	stage ranal-failure; trace gas-analysis; quantitative-analysis (en)
http://linked.open.../riv/klicoveSlovo	trace gas-analysis quantitative-analysis stage ranal-failure
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[A86A82B40DF9]
http://linked.open...i/riv/nazevZdroje	Rapid Communications in Mass Spectrometry
http://linked.open...in/vavai/riv/obor	CF
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Mass spectrometric and theoretical characterization of transient molecules A study of elementary processes in low-temperature and technologically oriented plasmas and the development of relevant diagnostic methods
http://linked.open...UplatneniVysledku	2003
http://linked.open...v/svazekPeriodika	17
http://linked.open...iv/tvurceVysledku	Smith, D. Španěl, Patrik Wang, T. Sule-Suso, J. El Haj, A.
http://linked.open...n/vavai/riv/zamer	Objasňování zákonitostí vztahů struktury a vlastností - zejména dynamiky a chemické reaktivity - látek a molekulárních systémů
issn	0951-4198
number of pages	6 (xsd:int)

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