About: Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster

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About: Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster Goto Sponge Distinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In many organisms reproduction is negatively correlated with lifespan. Juvenile hormone (JH) is currently considered to play a key role in the modulation of this trade-off in insects but the way it does so remains unknown. Complementary approaches in two models, the firebug P. apterus and the genetic workhorse Drosophila melanogaster, help to uncover these mechanisms. Hypothetically, JH might accelerate aging via its well-documented stimulating effect on reproduction. Combination of surgical interventions in Pyrrhocoris apterus demonstrated that egg production itself is not the mechanism by which JH accelerates aging. Yet, the genetic approach in D. melanogaster revealed that reproduction still seems to be central to the hormonal control of aging via hypothesized endocrine signals produced by the somatic gonad that are regulated by germ line stem cells. In many organisms reproduction is negatively correlated with lifespan. Juvenile hormone (JH) is currently considered to play a key role in the modulation of this trade-off in insects but the way it does so remains unknown. Complementary approaches in two models, the firebug P. apterus and the genetic workhorse Drosophila melanogaster, help to uncover these mechanisms. Hypothetically, JH might accelerate aging via its well-documented stimulating effect on reproduction. Combination of surgical interventions in Pyrrhocoris apterus demonstrated that egg production itself is not the mechanism by which JH accelerates aging. Yet, the genetic approach in D. melanogaster revealed that reproduction still seems to be central to the hormonal control of aging via hypothesized endocrine signals produced by the somatic gonad that are regulated by germ line stem cells. (en)
Title	Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster (en)
skos:prefLabel	Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster (en)
skos:notation	RIV/60077344:_____/11:00365249!RIV12-AV0-60077344
http://linked.open...avai/predkladatel	Biologické centrum AV ČR, v. v. i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA206/05/2222), P(GAP502/10/1612), Z(AV0Z50070508)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Hodková, Magdalena
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biologické centrum AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	219524
http://linked.open...ai/riv/idVysledku	RIV/60077344:_____/11:00365249
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Pyrrhocoris apterus; Drosophila melanogaster; endocrine control (en)
http://linked.open.../riv/klicoveSlovo	Pyrrhocoris apterus endocrine control Drosophila melanogaster
http://linked.open...ontrolniKodProRIV	[6A5B3D71CAA9]
http://linked.open...i/riv/mistoVydani	Oxford
http://linked.open...i/riv/nazevZdroje	Mechanisms of Life History Evolution. The Genetics and Physiology of Life History Traits and Trade-offs
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...v/pocetStranKnihy	478 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Endocrine regulation of longevity in an insect model Endocrine regulation of circadian clock genes in relation to aging in an insect model
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Hodková, Magdalena Tatar, M.
http://linked.open...n/vavai/riv/zamer	Study of the regulation of insect organism, dynamics of insect populations and function of insects in ecosystems
number of pages	9 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Oxford University Press
https://schema.org/isbn	978-0-19-956877-2
is http://linked.open...avai/riv/vysledek of	Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster Parallels in understanding the endocrine control of lifespan with the firebug Pyrrhocoris apterus and the fruit fly Drosophila melanogaster

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