About: Fucose-binding lectin from human pathogen Aspergillus fumigatus

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We have identified several lectin-like proteins in the recently sequenced genome of A. fumigatus. One of them has been characterized. The recombinant protein binding activities were determined by hemagglutination studies, glycan-array, surface plasmon resonance and isothermal titration calorimetry. The X-ray structure of AFL with histo-blood groups A, Lewis Y and a mixture of fucosylated disaccharides revealed different properties of individual binding sites of the lectin. We have identified several lectin-like proteins in the recently sequenced genome of A. fumigatus. One of them has been characterized. The recombinant protein binding activities were determined by hemagglutination studies, glycan-array, surface plasmon resonance and isothermal titration calorimetry. The X-ray structure of AFL with histo-blood groups A, Lewis Y and a mixture of fucosylated disaccharides revealed different properties of individual binding sites of the lectin. (en)
Title	Fucose-binding lectin from human pathogen Aspergillus fumigatus Fucose-binding lectin from human pathogen Aspergillus fumigatus (en)
skos:prefLabel	Fucose-binding lectin from human pathogen Aspergillus fumigatus Fucose-binding lectin from human pathogen Aspergillus fumigatus (en)
skos:notation	RIV/00216224:14740/11:00050298!RIV12-GA0-14740___
http://linked.open...avai/predkladatel	Středoevropský technologický institut
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA303/09/1168), P(ME08008), Z(MSM0021622413)
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Komárek, Jan Houser, Josef Kostlánová, Nikola Wimmerová, Michaela
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Středoevropský technologický institut
http://linked.open...dnocenehoVysledku	200479
http://linked.open...ai/riv/idVysledku	RIV/00216224:14740/11:00050298
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	lectin; fucose; opportunistic pathogen (en)
http://linked.open.../riv/klicoveSlovo	fucose opportunistic pathogen lectin
http://linked.open...ontrolniKodProRIV	[FBCD0001AE2E]
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Lectins from human pathogens - structure, function, engineering Design of Carbohydrates and Glycomimetics as Antibacterial and Antiviral Drugs
http://linked.open...UplatneniVysledku	2011
http://linked.open...iv/tvurceVysledku	Cioci, Gianluca Houser, Josef Imberty, Anne Komárek, Jan Kostlánová, Nikola Wimmerová, Michaela
http://linked.open...n/vavai/riv/zamer	Proteiny v metabolismu a při interakci organismů s prostředím
http://localhost/t...ganizacniJednotka	14740

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