About: Elliptinium

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Elliptinium
rdfs:subClassOf	Topoisomerase-II Inhibitor DNA Intercalating Agent
Has_Salt_Form	Elliptinium Acetate
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Elliptinium
UMLS_CUI	C0115685
CAS_Registry	58337-34-1
FDA_UNII_Code	1F1959S062
Contributing_Source	FDA
Chemical_Formula	C18H17N2O
Legacy_Concept_Name	Elliptinium
FULL_SYN	ElliptiniumPTNCI N-2-Methyl-9-hydroxyellipticiniumSNNCI 9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazoliumSNNCI NMHEABNCI ELLIPTINIUMPTFDA1F1959S062 9-Hydroxy-2-methylellipticiniumSNNCI
DEFINITION	A derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria vitensis, a plant with anti-cancer properties. As a topoisomerase II inhibitor and intercalating agent, elliptinium stabilizes the cleavable complex of topoisomerase II and induces DNA breakages, thereby inhibiting DNA replication and RNA and protein synthesis.NCI
code	C90495
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0089986
is Has_Free_Acid_Or_Base_Form of	Elliptinium Acetate

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