About: Elliptinium Acetate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Elliptinium Acetate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Elliptinium Acetate
NSC_Code
  • 264137
UMLS_CUI
  • C0100593
CAS_Registry
  • 58337-35-2
FDA_UNII_Code
  • H9B41234P4
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39231
PDQ_Closed_Trial_Search_ID
  • 39231
Chemical_Formula
  • C18H17N2O.C2H3O2
Legacy_Concept_Name
  • Elliptinium
FULL_SYN
  • 9-Hydroxy-2-methylellipticinium acetateSYDTPNSC0264137
  • 9-Hydroxy-2-methylellipticinium AcetateSNNCI
  • CeliptiumSYDTPNSC0264137
  • Elliptinium AcetatePTNCI
  • 9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazolium Acetate (Salt)SNNCI
  • 6H-Pyrido[4, 3-b]carbazolium, 9-hydroxy-2,5,11-trimethyl-acetate (salt)SYDTPNSC0264137
  • ELLIPTINIUM ACETATEPTFDAH9B41234P4
  • N-2-Methyl-9-hydroxyellipticinium AcetateSNNCI
  • CeliptiumBRNCI
DEFINITION
  • Acetate salt of elliptinium, a derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria vitensis, a plant with anti-cancer properties. As a topoisomerase II inhibitor and intercalating agent, elliptinium stabilizes the cleavable complex of topoisomerase II and induces DNA breakages, thereby inhibiting DNA replication and RNA and protein synthesis.NCI
code
  • C1367
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
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