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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Amotosalen
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Amotosalen
UMLS_CUI
  • C1136704
CAS_Registry
  • 161262-29-9
FDA_UNII_Code
  • K1LDZ0VBC0
Contributing_Source
  • FDA
Chemical_Formula
  • C17H19NO4
Legacy_Concept_Name
  • Amotosalen
FULL_SYN
  • AMOTOSALENPTFDAK1LDZ0VBC0
  • AmotosalenPTNCI
DEFINITION
  • A synthetic psoralen, light-activated DNA and RNA crosslinking agent, with protective activity against pathogens such as bacteria, viruses, protozoa, and leukocytes. Prior to administration amotosalen is added to plasma and platelets, then in vivo this agent penetrates pathogens and targets DNA and RNA. Upon activation by ultraviolet A light, this agent is able to form interstrand DNA and RNA crosslinks and prevents replication. Inactivation of leukocytes can prevent graft versus host disease upon transfusion.NCI
code
  • C76756
http://linked.open...y/mesh/hasConcept
is Has_Free_Acid_Or_Base_Form of
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