About: Vinflunine Ditartrate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Vinflunine Ditartrate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Vinflunine Ditartrate
UMLS_CUI
  • C2700251
CAS_Registry
  • 194468-36-5
FDA_UNII_Code
  • 33MG53C7XW
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of bladder cancer, lung cancer, and other types of cancer.NCI-GLOSS
Chemical_Formula
  • C45H54F2N4O8.2C4H6O6
Legacy_Concept_Name
  • Vinflunine_Ditartrate
FULL_SYN
  • VINFLUNINE DITARTRATEPTFDA33MG53C7XW
  • JavlorPTNCI-GLOSSCDR0000512884
  • Vinflunine DitartratePTNCI
DEFINITION
  • The ditartrate salt of vinflunine, a bi-fluorinated derivative of the semisynthetic vinca alkaloid vinorelbine with potential antimitotic and antineoplastic activities. Vinflunine binds to tubulin and inhibits tubulin assembly and disrupts microtubule assembly dynamics. This results in cell cycle arrest in mitosis and an induction of apoptosis.NCI
code
  • C76266
is Has_Salt_Form of
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