About: Mycophenolic Acid

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Mycophenolic Acid
rdfs:subClassOf	Inosine Monophosphate Dehydrogenase Inhibitor IMMUNE SUPPRESSANTS
Has_Salt_Form	MYCOPHENOLATE SODIUM
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Antibiotic Organic Chemical
Preferred_Name	Mycophenolic Acid
NSC_Code	129185
UMLS_CUI	C0026933
CAS_Registry	24280-93-1 483-60-3
Accepted_Therapeutic_Use_For	Prophylaxis of organ rejection after allogenic renal; cardiac; or hepatic transplants; psoriasis
FDA_UNII_Code	HU9DX48N0T
Contributing_Source	FDA
Chemical_Formula	C17H20O6
Legacy_Concept_Name	Mycophenolic_Acid
CHEBI_ID	CHEBI:168396
FULL_SYN	Lilly-68618CNNCI Mycophenolic AcidPTDCP30198 MPAABNCI 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)-SNNCI Mycophenolic AcidPTNCI MYCOPHENOLIC ACIDPTFDAHU9DX48N0T Acido micofenolicoSYNCI Ly 68618CNNCI 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-SNNCI MyforticBRNCI Acide mycophenoliqueSYNCI Acidum mycophenolicumSYNCI
DEFINITION	An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate mofetil. Mycophenolic acid inhibits inosine monophosphate dehydrogenase (IMPDH), preventing the formation of guanosine monophosphate and synthesis of lymphocyte DNA that results in inhibition of lymphocyte proliferation, antibody production, cellular adhesion, and migration of T and B lymphocytes. Mycophenolic acid also has antibacterial, antifungal, and antiviral activities. (NCI04)NCI
code	C673
sameAs	MYCOPHENOLIC ACID
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0014304
is Has_Free_Acid_Or_Base_Form of	MYCOPHENOLATE SODIUM
is sameAs of	MYCOPHENOLIC ACID MYCOPHENOLIC ACID

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