About: Mycophenolate Sodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Mycophenolate Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Mycophenolate Sodium
NSC_Code
  • 116072
UMLS_CUI
  • C1337395
CAS_Registry
  • 37415-62-6
FDA_UNII_Code
  • WX877SQI1G
Contributing_Source
  • FDA
Chemical_Formula
  • C17H19O6.Na
Legacy_Concept_Name
  • Mycophenolate_Sodium
FULL_SYN
  • MYCOPHENOLATE SODIUMPTFDAWX877SQI1G
  • 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, monosodium salt, (4E)-SNNCI
  • ERL 080CNNCI
  • ERL 080ACNNCI
  • Socium MycophenolateSYNCI
  • Mycophenolate SodiumPTNCI
DEFINITION
  • The sodium salt form of mycophenolic acid (MPA), with immunosuppressing activity. In vivo, the active molecule MPA reversibly inhibits inosine monophosphate dehydrogenase (IMPDH) which is needed for guanine monophosphate synthesis and stops the proliferation of B and T lymphocytes. Relative to other cell types, lypmocytes are highly dependent on salvage and de novo synthesis of guanine nucleotides, thus making these cells prone to MPA cytotoxicity.NCI
code
  • C66215
sameAs
is Has_Salt_Form of
is sameAs of
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