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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Donepezil
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Donepezil
UMLS_CUI
  • C0527316
CAS_Registry
  • 120014-06-4
FDA_UNII_Code
  • 8SSC91326P
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to treat Alzheimer disease and is being studied in the treatment of side effects caused by radiation therapy to the brain. It is a type of cholinesterase inhibitor.NCI-GLOSS
Chemical_Formula
  • C24H29NO3
Legacy_Concept_Name
  • Donepezil_Base
CHEBI_ID
  • CHEBI:53289
FULL_SYN
  • DONEPEZILPTFDA8SSC91326P
  • DonepezilPTNCI
  • donepezilPTNCI-GLOSSCDR0000044980
DEFINITION
  • The hydrochloride salt of a piperidine derivative with neurocognitive-enhancing activity. Donepezil reversibly inhibits acetylcholinesterase, thereby blocking the hydrolysis of the neurotransmitter acetylcholine and, consequently, increasing its activity. This agent may improve neurocognitive function in Alzheimer's disease, reduce sedation associated with opioid treatment of cancer pain, and improve neurocognitive function in patients who have received radiation therapy for primary brain tumors or brain metastases.NCI
code
  • C66874
sameAs
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