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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Olmesartan
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Olmesartan
UMLS_CUI
  • C1098320
CAS_Registry
  • 144689-24-7
FDA_UNII_Code
  • 8W1IQP3U10
Contributing_Source
  • FDA
Chemical_Formula
  • C24H26N6O3
Legacy_Concept_Name
  • Olmesartan
CHEBI_ID
  • CHEBI:48416
FULL_SYN
  • OLMESARTANPTFDA8W1IQP3U10
  • OlmesartanPTNCI
DEFINITION
  • A synthetic imidazole derivative and angiotensin II receptor antagonist with antihypertensive activity. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor subtype in vascular smooth muscle and adrenal gland, thereby competing with angiotensin II for binding to the AT1 receptor. This prevents angiotensin II-induced vasoconstriction and interferes with angiotensin II-mediated aldosterone secretion, thereby decreasing aldosterone production and preventing aldosterone-stimulated sodium retention and potassium excretion.NCI
code
  • C66253
sameAs
http://linked.open...y/mesh/hasConcept
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