About: Olmesartan Medoxomil     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Olmesartan Medoxomil
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Olmesartan Medoxomil
UMLS_CUI
  • C0386393
CAS_Registry
  • 144689-63-4
FDA_UNII_Code
  • 6M97XTV3HD
Contributing_Source
  • FDA
Chemical_Formula
  • C29H30N6O6
Legacy_Concept_Name
  • Olmesartan_Medoxomil
FULL_SYN
  • OLMESARTAN MEDOXOMILPTFDA6M97XTV3HD
  • 1H-Imidazole-5-carboxylic Acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl EsterSNNCI
  • Olmesartan MedoxomilPTDCP32062
  • CS 866CNNCI
  • BenicarBRNCI
  • Olmesartan MedoxomilPTNCI
DEFINITION
  • A synthetic imidazole derivative prodrug with an antihypertensive property. Upon hydrolysis, olmesartan medoxomil is converted to olmesartan. Olmesartan selectively binds to the angiotensin type 1 (AT1) receptor of angiotensin II in vascular smooth muscle and adrenal gland, thereby competing angiotensin II binding to the receptor. This prevents angiotensin II-induced vasoconstriction and decreases aldosterone production, thereby preventing aldosterone-stimulated sodium retention and potassium excretion.NCI
code
  • C47640
sameAs
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