About: Cyclothiazide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cyclothiazide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cyclothiazide
UMLS_CUI
  • C0056831
CAS_Registry
  • 2259-96-3
FDA_UNII_Code
  • P71U09G5BW
Contributing_Source
  • FDA
Chemical_Formula
  • C14H16ClN3O4S2
Legacy_Concept_Name
  • Cyclothiazide
CHEBI_ID
  • CHEBI:31448
FULL_SYN
  • CYCLOTHIAZIDEPTFDAP71U09G5BW
  • CyclothiazidePTNCI
DEFINITION
  • A benzothiadiazide belonging to the class of thiazide diuretics. Cyclothiazide is indicated as adjunctive therapy in edema and in the treatment of hypertension. In addition, this agent is capable of inhibiting rapid desensitization of the ionotropic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptors, thereby potentiating glutamate responses which may induce seizures activity. Cyclothiazide was also found to inhibit gamma-aminobutyric acid (GABA)-A receptors.NCI
code
  • C65358
sameAs
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