About: Carvedilol Phosphate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Carvedilol Phosphate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Carvedilol Phosphate
UMLS_CUI
  • C1815010
CAS_Registry
  • 610309-89-2
FDA_UNII_Code
  • EQT531S367
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat high blood pressure and certain heart problems. It is also being studied in the prevention and treatment of side effects caused by some anticancer drugs. Carvedilol phosphate blocks certain receptors on nerve cells and causes blood vessels to dilate (widen). It is a type of antihypertensive agent and a type of antianginal agent.NCI-GLOSS
Chemical_Formula
  • 2C24H26N2O4.H2O.2H3O4P
Legacy_Concept_Name
  • Carvedilol_Phosphate
FULL_SYN
  • CARVEDILOL PHOSPHATEPTFDAEQT531S367
  • carvedilol phosphatePTNCI-GLOSSCDR0000662931
  • Carvedilol PhosphatePTNCI
DEFINITION
  • The phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.NCI
code
  • C65292
sameAs
is Has_Salt_Form of
is sameAs of
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