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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Carvedilol
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Carvedilol
UMLS_CUI
  • C0719509
CAS_Registry
  • 72956-09-3
FDA_UNII_Code
  • 0K47UL67F2
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat high blood pressure and certain heart problems. It is also being studied in the prevention and treatment of side effects caused by some anticancer drugs. Coreg blocks certain receptors on nerve cells and causes blood vessels to dilate (widen). It is a type of antihypertensive agent and a type of antianginal agent.NCI-GLOSS
Chemical_Formula
  • C24H26N2O4
Legacy_Concept_Name
  • Carvedilol
CHEBI_ID
  • CHEBI:3441
FULL_SYN
  • CarvedilolPTDCP32052
  • CoregPTNCI-GLOSSCDR0000662933
  • CoregBRNCI
  • CARVEDILOLPTFDA0K47UL67F2
  • CarvedilolPTNCI
DEFINITION
  • A synthetic antihypertensive methoxyphenoxy- 2-propanol derivative with no intrinsic sympathomimetic activity, Carvedilol acts as a nonselective beta-adrenoceptor blocking agent (S(-) enantiomer) and as an alpha 1-adrenoceptor blocker (R(+) and S(-) enantiomers). Its acts more strongly on beta-receptors than on alpha 1-receptors, reduces peripheral vascular resistance by vasodilation, and prevents reflex tachycardia (beta-blockade) so that heart rate is either unchanged or decreased. Carvedilol also reduces renin release through beta-blockade. (NCI04)NCI
code
  • C28906
sameAs
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