About: Pegdinetanib     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pegdinetanib
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pegdinetanib
UMLS_CUI
  • C1831965
ALT_DEFINITION
  • A substance being studied in the treatment of cancer. CT-322 may prevent the growth of new blood vessels that tumors need to grow and may kill cancer cells. It is a type of vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor and a type of antiangiogenesis agent.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 575516
PDQ_Closed_Trial_Search_ID
  • 575516
Legacy_Concept_Name
  • CT-322
FULL_SYN
  • PegdinetanibPTNCI
  • CT-322PTNCI-GLOSSCDR0000600470
  • CT-322CNNCI
  • VEGFR-2 inhibitor CT-322PTNCI-GLOSSCDR0000600471
  • AngioceptBRNCI
  • BMS-844203CNNCI
  • AngioceptPTNCI-GLOSSCDR0000600472
DEFINITION
  • A pegylated form of a thermostable and protease resistant peptide targeting human vascular endothelial growth factor receptor-2 (VEGFR-2) with potential antiangiogenic activity. Derived from the 10th type III domain of human fibronectin and one of the natural ligands, pegdinetanib binds to VEGFR-2 and prevents activation of VEGFR-2 by other activating ligands. This may inhibit the growth of new tumor blood vessels.NCI
code
  • C62791
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 123 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software